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• W2587321025 abstract "SUMMARY Cardoso LSM, Martins CR, Tardelli MA- Effects of IntravenousLidocaine on the Pharmacodynamics of Rocuronium BACKGROUND AND OBJECTIVES : Rocuronium is an inter-mediate nondepolarizing neuromuscular blocker (NMB) withfaster onset and indicated in situations requiring rapid trachealintubation. Intravenous lidocaine is often used to decreasehemodynamic responses to tracheal intubation. The associa-tion of NMB to local anesthetics results in potentiation of NMBeffects. The purpose of this study was to evaluate the influenceof lidocaine on rocuronium’s pharmacodynamics determinedby acceleromyography. METHODS : Forty-six ASA I-II patients, aged 18 to 65 years,were randomly distributed in two groups (CG: control and LG:lidocaine). Rocuronium was given to all patients forneuromuscular block. LG received lidocaine (1.5 mg.kg -1 )3minutes before rocuronium. Neuromuscular function wasevaluated by adductor pollicis muscle response to TOF. AfterNMBinjection,timesforfirstTOFresponse(T 1 )toreach10and0% of baseline value and recover 25%, 75% and 95% of con-traction height (Dur" @default.
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• W2587321025 date "2005-01-01" @default.
• W2587321025 modified "2023-09-27" @default.
• W2587321025 title "Efeitos da Lidocaína por Via Venosa sobre a Farmacodinâmica do Rocurônio * Effects of Intravenous Lidocaine on the Pharmacodynamics of Rocuronium" @default.
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