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- W2587889473 abstract "Sodium polysulfides (Na2Sn, n > 1) as important raw materials in the chemical industry can afford hydrogen polysulfides (H2Sn, n > 1) under physiological conditions. Hydrogen polysulfides are important reactive sulfide species that play crucial roles in biological systems. The simple detection of H2Sn in solution and biosystems becomes very important as a consequence of the foregoing applications. Herein, we report a NIR fluorescent chemodosimeter, Cy-Sn, displaying turn-on fluorescence after reaction with H2Sn, which exhibits good selectivity and sensitivity in solution and biosystems. Moreover, it was applied successfully to monitor endogenous hydrogen polysulfides via the cystathionine γ-lyase (CSE) enzymatic pathway during inflammation and anti-inflammation in living RAW 264.7 cells. Mouse experiments indicated that this chemodosimeter has good potential to be employed in the imaging of living biosystems." @default.
- W2587889473 created "2017-02-24" @default.
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- W2587889473 date "2017-01-01" @default.
- W2587889473 modified "2023-10-13" @default.
- W2587889473 title "A NIR fluorescent chemodosimeter for imaging endogenous hydrogen polysulfides via the CSE enzymatic pathway" @default.
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- W2587889473 doi "https://doi.org/10.1039/c7tb00098g" @default.
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