FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2588009620> ?p ?o ?g. }

• W2588009620 endingPage "775" @default.
• W2588009620 startingPage "768" @default.
• W2588009620 abstract "Summary Killer immunoglobulin‐like receptors ( KIR s) regulate the activation of natural killer cells through their interaction with human leucocyte antigens ( HLA ). KIR and HLA loci are highly polymorphic, and certain HLA ‐ KIR combinations have been found to protect against viral infections. In this study, we analysed whether the KIR / HLA repertoire may influence the course of hepatitis B virus ( HBV ) infection. Fifty‐seven subjects with chronic hepatitis B ( CHB ), 44 subjects with resolved HBV infection and 60 healthy uninfected controls ( HC ) were genotyped for KIR and their HLA ligands. The frequency of the HLA ‐A‐Bw4 ligand group was higher in CHB (58%) than subjects with resolved infection (23%) (crude OR , 4.67; P <.001) and HC (10%) (crude OR , 12.38; P <.001). Similar results were obtained for the HLA ‐C2 ligand group, more frequent in CHB (84%), than subjects with resolved infection (70%) (crude OR , 2.24; P <.10) and HC (60%) (crude OR , 3.56; P <.01). Conversely, the frequency of KIR 2 DL 3 was lower in CHB (81%) than in subjects with resolved infection (98%) (crude OR , 0.10; P <.05). These results suggest a detrimental role of HLA ‐A‐Bw4 and HLA ‐C2 groups, which are associated with the development of CHB , and a protective role of KIR 2 DL 3. A stepwise variable selection procedure, based on multiple logistic regression analysis, identified these three predictive variables as the most relevant, featuring high specificity (90.9%) and positive predictive value (87.5%) for the development of CHB . Our results suggest that a combination of KIR / HLA gene/alleles is able to predict the outcome of HBV infection." @default.
• W2588009620 created "2017-02-24" @default.
• W2588009620 creator A5006712720 @default.
• W2588009620 creator A5008860706 @default.
• W2588009620 creator A5010219115 @default.
• W2588009620 creator A5010848508 @default.
• W2588009620 creator A5014181660 @default.
• W2588009620 creator A5015945590 @default.
• W2588009620 creator A5018846450 @default.
• W2588009620 creator A5028162881 @default.
• W2588009620 creator A5029938834 @default.
• W2588009620 creator A5033992629 @default.
• W2588009620 creator A5054433356 @default.
• W2588009620 creator A5057309081 @default.
• W2588009620 creator A5058464748 @default.
• W2588009620 creator A5059355764 @default.
• W2588009620 creator A5067975162 @default.
• W2588009620 creator A5075492332 @default.
• W2588009620 creator A5082733849 @default.
• W2588009620 creator A5089497961 @default.
• W2588009620 date "2017-05-05" @default.
• W2588009620 modified "2023-10-04" @default.
• W2588009620 title "KIR2DL3 and the KIR ligand groups HLA-A-Bw4 and HLA-C2 predict the outcome of hepatitis B virus infection" @default.
• W2588009620 cites W1524742538 @default.
• W2588009620 cites W1564121197 @default.
• W2588009620 cites W1968209119 @default.
• W2588009620 cites W1981215706 @default.
• W2588009620 cites W1987741171 @default.
• W2588009620 cites W1999468210 @default.
• W2588009620 cites W2011388528 @default.
• W2588009620 cites W2022915690 @default.
• W2588009620 cites W2027142061 @default.
• W2588009620 cites W2058321555 @default.
• W2588009620 cites W2073572679 @default.
• W2588009620 cites W2091370926 @default.
• W2588009620 cites W2095200251 @default.
• W2588009620 cites W2095603321 @default.
• W2588009620 cites W2102628901 @default.
• W2588009620 cites W2107749930 @default.
• W2588009620 cites W2120462202 @default.
• W2588009620 cites W2122132317 @default.
• W2588009620 cites W2124475984 @default.
• W2588009620 cites W2130854591 @default.
• W2588009620 cites W2141248446 @default.
• W2588009620 cites W2162665513 @default.
• W2588009620 cites W2171709048 @default.
• W2588009620 cites W2340384276 @default.
• W2588009620 cites W2342291952 @default.
• W2588009620 cites W4211026375 @default.
• W2588009620 doi "https://doi.org/10.1111/jvh.12698" @default.
• W2588009620 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28211154" @default.
• W2588009620 hasPublicationYear "2017" @default.
• W2588009620 type Work @default.
• W2588009620 sameAs 2588009620 @default.
• W2588009620 citedByCount "24" @default.
• W2588009620 countsByYear W25880096202017 @default.
• W2588009620 countsByYear W25880096202018 @default.
• W2588009620 countsByYear W25880096202019 @default.
• W2588009620 countsByYear W25880096202020 @default.
• W2588009620 countsByYear W25880096202021 @default.
• W2588009620 countsByYear W25880096202022 @default.
• W2588009620 countsByYear W25880096202023 @default.
• W2588009620 crossrefType "journal-article" @default.
• W2588009620 hasAuthorship W2588009620A5006712720 @default.
• W2588009620 hasAuthorship W2588009620A5008860706 @default.
• W2588009620 hasAuthorship W2588009620A5010219115 @default.
• W2588009620 hasAuthorship W2588009620A5010848508 @default.
• W2588009620 hasAuthorship W2588009620A5014181660 @default.
• W2588009620 hasAuthorship W2588009620A5015945590 @default.
• W2588009620 hasAuthorship W2588009620A5018846450 @default.
• W2588009620 hasAuthorship W2588009620A5028162881 @default.
• W2588009620 hasAuthorship W2588009620A5029938834 @default.
• W2588009620 hasAuthorship W2588009620A5033992629 @default.
• W2588009620 hasAuthorship W2588009620A5054433356 @default.
• W2588009620 hasAuthorship W2588009620A5057309081 @default.
• W2588009620 hasAuthorship W2588009620A5058464748 @default.
• W2588009620 hasAuthorship W2588009620A5059355764 @default.
• W2588009620 hasAuthorship W2588009620A5067975162 @default.
• W2588009620 hasAuthorship W2588009620A5075492332 @default.
• W2588009620 hasAuthorship W2588009620A5082733849 @default.
• W2588009620 hasAuthorship W2588009620A5089497961 @default.
• W2588009620 hasConcept C116569031 @default.
• W2588009620 hasConcept C126322002 @default.
• W2588009620 hasConcept C147483822 @default.
• W2588009620 hasConcept C159047783 @default.
• W2588009620 hasConcept C170493617 @default.
• W2588009620 hasConcept C188280979 @default.
• W2588009620 hasConcept C203014093 @default.
• W2588009620 hasConcept C2522874641 @default.
• W2588009620 hasConcept C2776408679 @default.
• W2588009620 hasConcept C2780593183 @default.
• W2588009620 hasConcept C71924100 @default.
• W2588009620 hasConcept C86803240 @default.
• W2588009620 hasConceptScore W2588009620C116569031 @default.
• W2588009620 hasConceptScore W2588009620C126322002 @default.
• W2588009620 hasConceptScore W2588009620C147483822 @default.
• W2588009620 hasConceptScore W2588009620C159047783 @default.
• W2588009620 hasConceptScore W2588009620C170493617 @default.

• next