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• W2588084589 abstract "Summary Post‐traumatic epilepsy ( PTE ) is a relatively underappreciated condition that can develop as a secondary consequence following traumatic brain injury ( TBI ). The aim of this rapid evidence review is to provide a synthesis of existing evidence on the effectiveness of treatment interventions for the prevention of PTE in people who have suffered a moderate/severe TBI to increase awareness and understanding among consumers. Electronic medical databases (n = 5) and gray literature published between January 2010 and April 2015 were searched for studies on the management of PTE . Twenty‐two eligible studies were identified that met the inclusion criteria. No evidence was found for the effectiveness of any pharmacological treatments in the prevention or treatment of symptomatic seizures in adults with PTE . However, limited high‐level evidence for the effectiveness of the antiepileptic drug levetiracetam was identified for PTE in children. Low‐level evidence was identified for nonpharmacological interventions in significantly reducing seizures in patients with PTE , but only in a minority of cases, requiring further high‐level studies to confirm the results. This review provides an opportunity for researchers and health service professionals to better understand the underlying pathophysiology of PTE to develop novel, more effective therapeutic targets and to improve the quality of life of people with this condition." @default.
• W2588084589 created "2017-02-24" @default.
• W2588084589 creator A5021022034 @default.
• W2588084589 creator A5026245988 @default.
• W2588084589 creator A5079459105 @default.
• W2588084589 date "2017-03-17" @default.
• W2588084589 modified "2023-10-11" @default.
• W2588084589 title "Management of post-traumatic epilepsy: An evidence review over the last 5 years and future directions" @default.
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• W2588084589 doi "https://doi.org/10.1002/epi4.12049" @default.
• W2588084589 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5719843" @default.
• W2588084589 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29588942" @default.
• W2588084589 hasPublicationYear "2017" @default.
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