Matches in SemOpenAlex for { <https://semopenalex.org/work/W2588143818> ?p ?o ?g. }
- W2588143818 endingPage "2471" @default.
- W2588143818 startingPage "2467" @default.
- W2588143818 abstract "BACKGROUND Smoking is suspected to not only be a risk factor for chronic myeloid leukemia but an adverse prognostic factor for the disease as well. The objective of the current study was to investigate the impact of smoking on survival and progression to advanced phases of disease. METHODS Based on the data of the German CML Study IV, the authors analyzed the effect of smoking using a multivariate Cox model with the addition of the European Treatment and Outcome Study (EUTOS) long-term survival score variables of age, spleen size, thrombocytes, and peripheral blasts as well as sex, comorbidities, and type of treatment center. RESULTS The 8-year survival probability was 87% for a nonsmoking patient and 83% for a patient who smoked. The authors noted a 2.08-times higher risk of death for smokers in comparison with nonsmokers and a 2.11-times higher cause-specific hazard of disease progression. An interaction between smoking and age was found in the model for survival. No significant difference with regard to molecular response was observed. CONCLUSIONS Even when considering differences in socioeconomic status and lifestyle between patients who smoke and nonsmokers, the current analysis demonstrated that smoking also might affect disease biology. The results of the current study indicate that patients with chronic myeloid leukemia, in particular those aged <60 years, should be encouraged to quit smoking. Cancer 2017;123:2467–71. © 2017 American Cancer Society." @default.
- W2588143818 created "2017-02-24" @default.
- W2588143818 creator A5006284475 @default.
- W2588143818 creator A5013024565 @default.
- W2588143818 creator A5016147985 @default.
- W2588143818 creator A5022163234 @default.
- W2588143818 creator A5066994665 @default.
- W2588143818 creator A5069437715 @default.
- W2588143818 creator A5084493873 @default.
- W2588143818 creator A5086462994 @default.
- W2588143818 date "2017-02-13" @default.
- W2588143818 modified "2023-10-02" @default.
- W2588143818 title "Smokers with chronic myeloid leukemia are at a higher risk of disease progression and premature death" @default.
- W2588143818 cites W1493855295 @default.
- W2588143818 cites W1836949740 @default.
- W2588143818 cites W1865841947 @default.
- W2588143818 cites W1966714873 @default.
- W2588143818 cites W1977998749 @default.
- W2588143818 cites W1998406030 @default.
- W2588143818 cites W2000445173 @default.
- W2588143818 cites W2010678043 @default.
- W2588143818 cites W2016455125 @default.
- W2588143818 cites W2021009149 @default.
- W2588143818 cites W2027038862 @default.
- W2588143818 cites W2056520181 @default.
- W2588143818 cites W2057827171 @default.
- W2588143818 cites W2070593966 @default.
- W2588143818 cites W2077373114 @default.
- W2588143818 cites W2087765764 @default.
- W2588143818 cites W2097321013 @default.
- W2588143818 cites W2099747692 @default.
- W2588143818 cites W2112810605 @default.
- W2588143818 cites W2115353260 @default.
- W2588143818 cites W2135271710 @default.
- W2588143818 cites W2144514960 @default.
- W2588143818 cites W2156804290 @default.
- W2588143818 cites W2166990706 @default.
- W2588143818 cites W2282339584 @default.
- W2588143818 doi "https://doi.org/10.1002/cncr.30636" @default.
- W2588143818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28192602" @default.
- W2588143818 hasPublicationYear "2017" @default.
- W2588143818 type Work @default.
- W2588143818 sameAs 2588143818 @default.
- W2588143818 citedByCount "16" @default.
- W2588143818 countsByYear W25881438182017 @default.
- W2588143818 countsByYear W25881438182018 @default.
- W2588143818 countsByYear W25881438182019 @default.
- W2588143818 countsByYear W25881438182020 @default.
- W2588143818 countsByYear W25881438182021 @default.
- W2588143818 countsByYear W25881438182022 @default.
- W2588143818 countsByYear W25881438182023 @default.
- W2588143818 crossrefType "journal-article" @default.
- W2588143818 hasAuthorship W2588143818A5006284475 @default.
- W2588143818 hasAuthorship W2588143818A5013024565 @default.
- W2588143818 hasAuthorship W2588143818A5016147985 @default.
- W2588143818 hasAuthorship W2588143818A5022163234 @default.
- W2588143818 hasAuthorship W2588143818A5066994665 @default.
- W2588143818 hasAuthorship W2588143818A5069437715 @default.
- W2588143818 hasAuthorship W2588143818A5084493873 @default.
- W2588143818 hasAuthorship W2588143818A5086462994 @default.
- W2588143818 hasBestOaLocation W25881438181 @default.
- W2588143818 hasConcept C121608353 @default.
- W2588143818 hasConcept C126322002 @default.
- W2588143818 hasConcept C143998085 @default.
- W2588143818 hasConcept C203014093 @default.
- W2588143818 hasConcept C207103383 @default.
- W2588143818 hasConcept C2778461978 @default.
- W2588143818 hasConcept C2778729363 @default.
- W2588143818 hasConcept C2779134260 @default.
- W2588143818 hasConcept C38180746 @default.
- W2588143818 hasConcept C44249647 @default.
- W2588143818 hasConcept C50382708 @default.
- W2588143818 hasConcept C50440223 @default.
- W2588143818 hasConcept C71924100 @default.
- W2588143818 hasConceptScore W2588143818C121608353 @default.
- W2588143818 hasConceptScore W2588143818C126322002 @default.
- W2588143818 hasConceptScore W2588143818C143998085 @default.
- W2588143818 hasConceptScore W2588143818C203014093 @default.
- W2588143818 hasConceptScore W2588143818C207103383 @default.
- W2588143818 hasConceptScore W2588143818C2778461978 @default.
- W2588143818 hasConceptScore W2588143818C2778729363 @default.
- W2588143818 hasConceptScore W2588143818C2779134260 @default.
- W2588143818 hasConceptScore W2588143818C38180746 @default.
- W2588143818 hasConceptScore W2588143818C44249647 @default.
- W2588143818 hasConceptScore W2588143818C50382708 @default.
- W2588143818 hasConceptScore W2588143818C50440223 @default.
- W2588143818 hasConceptScore W2588143818C71924100 @default.
- W2588143818 hasFunder F4320323556 @default.
- W2588143818 hasIssue "13" @default.
- W2588143818 hasLocation W25881438181 @default.
- W2588143818 hasLocation W25881438182 @default.
- W2588143818 hasOpenAccess W2588143818 @default.
- W2588143818 hasPrimaryLocation W25881438181 @default.
- W2588143818 hasRelatedWork W2001972347 @default.
- W2588143818 hasRelatedWork W2052052878 @default.
- W2588143818 hasRelatedWork W2120574916 @default.
- W2588143818 hasRelatedWork W2493051678 @default.
- W2588143818 hasRelatedWork W2607758844 @default.