FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2588341785> ?p ?o ?g. }

• W2588341785 endingPage "e0172138" @default.
• W2588341785 startingPage "e0172138" @default.
• W2588341785 abstract "Background Essential oils from the aerial parts (leaves, twigs and berries) of Pistacia lentiscus (PLEO) have been well characterized for their antibacterial and anti-inflammatory properties; however, poor information exists on their potential anticancer activity. Methods Increasing concentrations of PLEO (0.01–0.1% v/v, 80–800 μg/ml) were administered to a wide variety of cultured cancer cells from breast, cervix, colon, liver, lung, prostate, and thyroid carcinomas. Fibroblasts were also included as healthy control cells. Cell viability was monitored by WST-8 assay up to 72 hours after PLEO administration. The intracellular formation of reactive oxygen species (ROS), the induction of apoptosis, and the enhancement of chemotherapeutic drug cytotoxicity by PLEO were further investigated in the most responsive cancer cell line. Results A dose-dependent reduction of tumor cell viability was observed upon PLEO exposure; while no cytotoxic effect was revealed in healthy fibroblasts. FTC-133 thyroid cancer cells were found to be the most sensitive cells to PLEO treatment; accordingly, an intracellular accumulation of ROS and an activation of both the extrinsic and intrinsic apoptotic pathways were evidenced in FTC-133 cells after PLEO administration. Furthermore, the cytotoxic effect of the antineoplastic drugs cisplatin, 5-fluorouracil and etoposide was enhanced in PLEO-exposed FTC-133 cells. Conclusion Taking into account its mode of action, PLEO might be considered as a promising source of natural antitumor agents which might have therapeutic potential in integrated oncology." @default.
• W2588341785 created "2017-02-24" @default.
• W2588341785 creator A5000316085 @default.
• W2588341785 creator A5017831650 @default.
• W2588341785 creator A5019834873 @default.
• W2588341785 creator A5022034613 @default.
• W2588341785 date "2017-02-14" @default.
• W2588341785 modified "2023-10-18" @default.
• W2588341785 title "Oxidative stress and apoptosis induction in human thyroid carcinoma cells exposed to the essential oil from Pistacia lentiscus aerial parts" @default.
• W2588341785 cites W13943305 @default.
• W2588341785 cites W1496088695 @default.
• W2588341785 cites W1557730305 @default.
• W2588341785 cites W1629950689 @default.
• W2588341785 cites W1753271690 @default.
• W2588341785 cites W1971858669 @default.
• W2588341785 cites W1996972040 @default.
• W2588341785 cites W2004494332 @default.
• W2588341785 cites W2041261502 @default.
• W2588341785 cites W2044638102 @default.
• W2588341785 cites W2046062465 @default.
• W2588341785 cites W2047759272 @default.
• W2588341785 cites W2085846119 @default.
• W2588341785 cites W2090065585 @default.
• W2588341785 cites W2103440521 @default.
• W2588341785 cites W2104453266 @default.
• W2588341785 cites W2105248627 @default.
• W2588341785 cites W2114472928 @default.
• W2588341785 cites W2122910156 @default.
• W2588341785 cites W2128635872 @default.
• W2588341785 cites W2144248079 @default.
• W2588341785 cites W2156408542 @default.
• W2588341785 cites W2157476886 @default.
• W2588341785 cites W2168830673 @default.
• W2588341785 cites W2337519696 @default.
• W2588341785 cites W2527031680 @default.
• W2588341785 cites W2546905330 @default.
• W2588341785 cites W4293247451 @default.
• W2588341785 cites W89080567 @default.
• W2588341785 doi "https://doi.org/10.1371/journal.pone.0172138" @default.
• W2588341785 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5308852" @default.
• W2588341785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28196126" @default.
• W2588341785 hasPublicationYear "2017" @default.
• W2588341785 type Work @default.
• W2588341785 sameAs 2588341785 @default.
• W2588341785 citedByCount "40" @default.
• W2588341785 countsByYear W25883417852017 @default.
• W2588341785 countsByYear W25883417852018 @default.
• W2588341785 countsByYear W25883417852019 @default.
• W2588341785 countsByYear W25883417852020 @default.
• W2588341785 countsByYear W25883417852021 @default.
• W2588341785 countsByYear W25883417852022 @default.
• W2588341785 countsByYear W25883417852023 @default.
• W2588341785 crossrefType "journal-article" @default.
• W2588341785 hasAuthorship W2588341785A5000316085 @default.
• W2588341785 hasAuthorship W2588341785A5017831650 @default.
• W2588341785 hasAuthorship W2588341785A5019834873 @default.
• W2588341785 hasAuthorship W2588341785A5022034613 @default.
• W2588341785 hasBestOaLocation W25883417851 @default.
• W2588341785 hasConcept C109316439 @default.
• W2588341785 hasConcept C121608353 @default.
• W2588341785 hasConcept C126322002 @default.
• W2588341785 hasConcept C154317977 @default.
• W2588341785 hasConcept C185592680 @default.
• W2588341785 hasConcept C190283241 @default.
• W2588341785 hasConcept C202751555 @default.
• W2588341785 hasConcept C2776151105 @default.
• W2588341785 hasConcept C48349386 @default.
• W2588341785 hasConcept C502942594 @default.
• W2588341785 hasConcept C53227056 @default.
• W2588341785 hasConcept C55493867 @default.
• W2588341785 hasConcept C71924100 @default.
• W2588341785 hasConcept C79879829 @default.
• W2588341785 hasConcept C86803240 @default.
• W2588341785 hasConcept C95444343 @default.
• W2588341785 hasConcept C96232424 @default.
• W2588341785 hasConcept C98274493 @default.
• W2588341785 hasConceptScore W2588341785C109316439 @default.
• W2588341785 hasConceptScore W2588341785C121608353 @default.
• W2588341785 hasConceptScore W2588341785C126322002 @default.
• W2588341785 hasConceptScore W2588341785C154317977 @default.
• W2588341785 hasConceptScore W2588341785C185592680 @default.
• W2588341785 hasConceptScore W2588341785C190283241 @default.
• W2588341785 hasConceptScore W2588341785C202751555 @default.
• W2588341785 hasConceptScore W2588341785C2776151105 @default.
• W2588341785 hasConceptScore W2588341785C48349386 @default.
• W2588341785 hasConceptScore W2588341785C502942594 @default.
• W2588341785 hasConceptScore W2588341785C53227056 @default.
• W2588341785 hasConceptScore W2588341785C55493867 @default.
• W2588341785 hasConceptScore W2588341785C71924100 @default.
• W2588341785 hasConceptScore W2588341785C79879829 @default.
• W2588341785 hasConceptScore W2588341785C86803240 @default.
• W2588341785 hasConceptScore W2588341785C95444343 @default.
• W2588341785 hasConceptScore W2588341785C96232424 @default.
• W2588341785 hasConceptScore W2588341785C98274493 @default.
• W2588341785 hasIssue "2" @default.
• W2588341785 hasLocation W25883417851 @default.
• W2588341785 hasLocation W25883417852 @default.
• W2588341785 hasLocation W25883417853 @default.

• next