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• W2588358224 abstract "Background : Transfusion-transmissible infections remain a major public health problem in developing countries. Epidemiological reports have documented that the risk of transmission of viral infections has been decreased in countries where continuous and rigorous screening of all donated blood is carried out. Therefore, the aim of this study was to assess the sero-prevalence of transfusion-transmissible viral infections among blood donors. Methods: A retrospective study was conducted among blood donors over three year’s period. Data was collected from records of North Gondar District Blood Bank. Data were cross-checked for completeness, entered and analyzed using SPSS version 20 software. Descriptive statistics were done and presented in percentages. Both bivariate and multivariate logistic regression analyses were done to determine statistical associations. P value < 0.05 was considered statistically significant. Result: A total of 6471 blood donors were enrolled; of whom 5311(82.1%) were males. Overall, 424 (6.55%) donors have shown serological evidence for at least one transfusion-transmissible viral infections. About 233(3.6%), 145(2.2%) and 51(0.8%) of those donors were sero-positive for HBsAg, HIV and HCV test respectively. Four (0.06%) of the study participants had shown co-infections: 3(75%) with HBV-HCV and 1(25%) with HIV-HBV-HCV. The highest sero-prevalence of HBV (5.0%), HIV (3.9%) and HCV (1.9%) were found among donors aged older than 45 years old. In multivariate logistic regression analysis occupation was significantly associated with HBV infection. Moreover, occupation and age have shown statistically significant association with HIV and HCV infection. Conclusion and recommendation: The overall sero-prevalence of transfusion-transmissible viral infections were still high in the study area with predominant in males and replacement donors. Hence, it demands more vigilance in routine screening of donated blood prior to transfusion, and design tailored control and prevention strategies to reduce the burden of transfusion-transmissible viral infections. Key words: Blood donors, Ethiopia, HBV, HCV, HIV, Transfusion-transmissible viral infections" @default.
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• W2588358224 date "2017-01-03" @default.
• W2588358224 modified "2023-09-27" @default.
• W2588358224 title "Transfusion-transmissible viral infections among blood donors at North Gondar District Blood Bank, Northwest Ethiopia: A three year retrospective study" @default.
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