FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2588641161> ?p ?o ?g. }

• W2588641161 endingPage "725" @default.
• W2588641161 startingPage "717" @default.
• W2588641161 abstract "Early-stage lung cancer represents a key focus of numerous multicenter clinical trials, but common exclusion criteria such as a prior cancer diagnosis may limit enrollment. We examined the prevalence and prognostic impact of a prior cancer diagnosis among patients with early-stage lung cancer.We identified patients>65 years of age with early-stage lung cancer diagnosed 1996-2009 in the Surveillance, Epidemiology, and End Results-Medicare linked database. Prior cancers were characterized by type, stage, and timing with respect to the lung cancer diagnosis. All-cause and lung cancer specific-survival rates were compared between patients with and without prior cancer using Cox regression analyses and propensity scores.Among 42,910 patients with early-stage lung cancer, one-fifth (21%) had a prior cancer. The most common prior cancers were prostate (21%), breast (18%), gastrointestinal (17%), and other genitourinary (15%). Most prior cancers were localized, and 61% were diagnosed within 5 years of the lung cancer diagnosis. There was no difference in all-cause survival between patients with and without prior cancer (hazard ratio [HR] 1.01; P=0.52). Lung cancer specific survival was improved among patients with prior cancer (HR 0.79; P<0.001).A prior cancer history may exclude a substantial proportion of patients with early-stage lung cancer from enrollment in clinical trials. Without adverse effect on clinical outcomes, inclusion of patients age >65 years with prior cancer in clinical trials should be considered to improve study accrual, completion rates, and generalizability." @default.
• W2588641161 created "2017-02-24" @default.
• W2588641161 creator A5042216129 @default.
• W2588641161 creator A5049648936 @default.
• W2588641161 creator A5054844187 @default.
• W2588641161 creator A5055537555 @default.
• W2588641161 creator A5091746173 @default.
• W2588641161 date "2017-02-14" @default.
• W2588641161 modified "2023-10-15" @default.
• W2588641161 title "Revisiting a longstanding clinical trial exclusion criterion: impact of prior cancer in early-stage lung cancer" @default.
• W2588641161 cites W1995002313 @default.
• W2588641161 cites W1997224801 @default.
• W2588641161 cites W2000445173 @default.
• W2588641161 cites W2005356510 @default.
• W2588641161 cites W2006237276 @default.
• W2588641161 cites W2008344757 @default.
• W2588641161 cites W2014516834 @default.
• W2588641161 cites W2018719867 @default.
• W2588641161 cites W2028442196 @default.
• W2588641161 cites W2029941278 @default.
• W2588641161 cites W2039764078 @default.
• W2588641161 cites W2055308718 @default.
• W2588641161 cites W2057041398 @default.
• W2588641161 cites W2064665507 @default.
• W2588641161 cites W2074048861 @default.
• W2588641161 cites W2075806628 @default.
• W2588641161 cites W2086811674 @default.
• W2588641161 cites W2088720324 @default.
• W2588641161 cites W2101814490 @default.
• W2588641161 cites W2102922616 @default.
• W2588641161 cites W2111925213 @default.
• W2588641161 cites W2128213210 @default.
• W2588641161 cites W2144630462 @default.
• W2588641161 cites W2145601586 @default.
• W2588641161 cites W2147485520 @default.
• W2588641161 cites W2149127322 @default.
• W2588641161 cites W2157520038 @default.
• W2588641161 cites W2160144478 @default.
• W2588641161 cites W2162018143 @default.
• W2588641161 cites W2162361175 @default.
• W2588641161 cites W2165624841 @default.
• W2588641161 cites W2169838621 @default.
• W2588641161 cites W2170552969 @default.
• W2588641161 cites W2226419169 @default.
• W2588641161 cites W2310092497 @default.
• W2588641161 cites W2418550904 @default.
• W2588641161 cites W4250849363 @default.
• W2588641161 doi "https://doi.org/10.1038/bjc.2017.27" @default.
• W2588641161 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5355931" @default.
• W2588641161 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28196065" @default.
• W2588641161 hasPublicationYear "2017" @default.
• W2588641161 type Work @default.
• W2588641161 sameAs 2588641161 @default.
• W2588641161 citedByCount "50" @default.
• W2588641161 countsByYear W25886411612017 @default.
• W2588641161 countsByYear W25886411612018 @default.
• W2588641161 countsByYear W25886411612019 @default.
• W2588641161 countsByYear W25886411612020 @default.
• W2588641161 countsByYear W25886411612021 @default.
• W2588641161 countsByYear W25886411612022 @default.
• W2588641161 countsByYear W25886411612023 @default.
• W2588641161 crossrefType "journal-article" @default.
• W2588641161 hasAuthorship W2588641161A5042216129 @default.
• W2588641161 hasAuthorship W2588641161A5049648936 @default.
• W2588641161 hasAuthorship W2588641161A5054844187 @default.
• W2588641161 hasAuthorship W2588641161A5055537555 @default.
• W2588641161 hasAuthorship W2588641161A5091746173 @default.
• W2588641161 hasBestOaLocation W25886411611 @default.
• W2588641161 hasConcept C121608353 @default.
• W2588641161 hasConcept C126322002 @default.
• W2588641161 hasConcept C143998085 @default.
• W2588641161 hasConcept C146357865 @default.
• W2588641161 hasConcept C151730666 @default.
• W2588641161 hasConcept C207103383 @default.
• W2588641161 hasConcept C2776256026 @default.
• W2588641161 hasConcept C2777405583 @default.
• W2588641161 hasConcept C2778321237 @default.
• W2588641161 hasConcept C2780192828 @default.
• W2588641161 hasConcept C44249647 @default.
• W2588641161 hasConcept C530470458 @default.
• W2588641161 hasConcept C535046627 @default.
• W2588641161 hasConcept C71924100 @default.
• W2588641161 hasConcept C86803240 @default.
• W2588641161 hasConceptScore W2588641161C121608353 @default.
• W2588641161 hasConceptScore W2588641161C126322002 @default.
• W2588641161 hasConceptScore W2588641161C143998085 @default.
• W2588641161 hasConceptScore W2588641161C146357865 @default.
• W2588641161 hasConceptScore W2588641161C151730666 @default.
• W2588641161 hasConceptScore W2588641161C207103383 @default.
• W2588641161 hasConceptScore W2588641161C2776256026 @default.
• W2588641161 hasConceptScore W2588641161C2777405583 @default.
• W2588641161 hasConceptScore W2588641161C2778321237 @default.
• W2588641161 hasConceptScore W2588641161C2780192828 @default.
• W2588641161 hasConceptScore W2588641161C44249647 @default.
• W2588641161 hasConceptScore W2588641161C530470458 @default.
• W2588641161 hasConceptScore W2588641161C535046627 @default.
• W2588641161 hasConceptScore W2588641161C71924100 @default.
• W2588641161 hasConceptScore W2588641161C86803240 @default.

• next