FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2588681701> ?p ?o ?g. }

• W2588681701 abstract "There is paucity data on the association of vitamin D deficiency (VDD) and active tuberculosis (TB) in southern Africa where the human immunodeficiency virus (HIV) is co-endemic. We examined the association of serum vitamin D concentrations with active pulmonary tuberculosis (PTB) in HIV-infected (n = 284) and uninfected (n = 267) Black Zimbabweans, in Harare, Zimbabwe. We conducted a cross-sectional study of 551 participants comprising 145 HIV+/PTB +, 139 HIV+/PTB−, 134 HIV−/PTB+ and 133 HIV−/PTB−. PTB status was confirmed using sputum by culture, or smear microscopy, or GeneXpert MTB/RIF. Serum 25-hydroxyvitamin D (25(OH)D) concentrations were measured using a competitive chemiluminescent immunoassay prior to commencement of anti-TB treatment. In all four groups, the median vitamin D concentrations were above the 20 ng/ml cut off for VDD. However, the median vitamin D concentrations in all the four groups were below the cut off for vitamin D sufficiency ≥30 ng/ml. The median vitamin D concentrations were significantly higher in PTB+ cases; 24.2 ng/ml (IQR: 18.8–32.0) compared to PTB− controls 20.9 ng/ml (IQR: 17.1–26.9), p < 0.0001 regardless of HIV status. The HIV+/PTB+ group had the highest median vitamin D concentration (25.3 (IQR: 18.0–33.7 ng/ml) whilst the HIV+/PTB− group had the lowest; 20.4 ng/ml (IQR: 14.6–26.9), p = 0.0003. Vitamin D concentration <30 ng/ml was associated with 43% lower odds of being PTB+ OR 0.57 (95% CI 0.35–0.89). Our results are not in agreement with the generally accepted hypothesis that VDD is associated with active PTB. To the contrary our results showed an association of higher vitamin D concentrations with active TB irrespective of HIV status. Although findings from the available pool of case control studies remain inconsistent, the results from the current study provide further rationale for larger-scale, prospectively designed studies to evaluate whether sufficient vitamin D concentrations do indeed precede the development of active PTB in our setting." @default.
• W2588681701 created "2017-02-24" @default.
• W2588681701 creator A5032837581 @default.
• W2588681701 creator A5042702752 @default.
• W2588681701 creator A5050659589 @default.
• W2588681701 creator A5064093776 @default.
• W2588681701 creator A5078563557 @default.
• W2588681701 creator A5080293779 @default.
• W2588681701 creator A5082438184 @default.
• W2588681701 creator A5083214254 @default.
• W2588681701 date "2017-02-13" @default.
• W2588681701 modified "2023-10-10" @default.
• W2588681701 title "Association of high serum vitamin D concentrations with active pulmonary TB in an HIV co-endemic setting, Harare, Zimbabwe" @default.
• W2588681701 cites W108787254 @default.
• W2588681701 cites W1559389386 @default.
• W2588681701 cites W1672397093 @default.
• W2588681701 cites W1897274595 @default.
• W2588681701 cites W1927671826 @default.
• W2588681701 cites W1964139383 @default.
• W2588681701 cites W1972181361 @default.
• W2588681701 cites W1991851194 @default.
• W2588681701 cites W1992048965 @default.
• W2588681701 cites W2003745777 @default.
• W2588681701 cites W2022519224 @default.
• W2588681701 cites W2033516350 @default.
• W2588681701 cites W2048030072 @default.
• W2588681701 cites W2076649068 @default.
• W2588681701 cites W2077089413 @default.
• W2588681701 cites W2078520607 @default.
• W2588681701 cites W2084954530 @default.
• W2588681701 cites W2085142442 @default.
• W2588681701 cites W2092073698 @default.
• W2588681701 cites W2102354280 @default.
• W2588681701 cites W2118475627 @default.
• W2588681701 cites W2118540989 @default.
• W2588681701 cites W2121256372 @default.
• W2588681701 cites W2121961071 @default.
• W2588681701 cites W2124070987 @default.
• W2588681701 cites W2126736305 @default.
• W2588681701 cites W2134049678 @default.
• W2588681701 cites W2138518467 @default.
• W2588681701 cites W2141094416 @default.
• W2588681701 cites W2154326381 @default.
• W2588681701 cites W2155675122 @default.
• W2588681701 cites W2277404544 @default.
• W2588681701 cites W2281691715 @default.
• W2588681701 cites W2294971061 @default.
• W2588681701 cites W2341690775 @default.
• W2588681701 cites W2555924635 @default.
• W2588681701 doi "https://doi.org/10.1186/s12879-017-2243-x" @default.
• W2588681701 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5307645" @default.
• W2588681701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28193202" @default.
• W2588681701 hasPublicationYear "2017" @default.
• W2588681701 type Work @default.
• W2588681701 sameAs 2588681701 @default.
• W2588681701 citedByCount "7" @default.
• W2588681701 countsByYear W25886817012018 @default.
• W2588681701 countsByYear W25886817012019 @default.
• W2588681701 countsByYear W25886817012020 @default.
• W2588681701 countsByYear W25886817012021 @default.
• W2588681701 countsByYear W25886817012023 @default.
• W2588681701 crossrefType "journal-article" @default.
• W2588681701 hasAuthorship W2588681701A5032837581 @default.
• W2588681701 hasAuthorship W2588681701A5042702752 @default.
• W2588681701 hasAuthorship W2588681701A5050659589 @default.
• W2588681701 hasAuthorship W2588681701A5064093776 @default.
• W2588681701 hasAuthorship W2588681701A5078563557 @default.
• W2588681701 hasAuthorship W2588681701A5080293779 @default.
• W2588681701 hasAuthorship W2588681701A5082438184 @default.
• W2588681701 hasAuthorship W2588681701A5083214254 @default.
• W2588681701 hasBestOaLocation W25886817011 @default.
• W2588681701 hasConcept C124490489 @default.
• W2588681701 hasConcept C126322002 @default.
• W2588681701 hasConcept C142052008 @default.
• W2588681701 hasConcept C142724271 @default.
• W2588681701 hasConcept C156957248 @default.
• W2588681701 hasConcept C185032368 @default.
• W2588681701 hasConcept C203014093 @default.
• W2588681701 hasConcept C2776301714 @default.
• W2588681701 hasConcept C2776940978 @default.
• W2588681701 hasConcept C2779740938 @default.
• W2588681701 hasConcept C2781069245 @default.
• W2588681701 hasConcept C3013748606 @default.
• W2588681701 hasConcept C71924100 @default.
• W2588681701 hasConcept C90924648 @default.
• W2588681701 hasConceptScore W2588681701C124490489 @default.
• W2588681701 hasConceptScore W2588681701C126322002 @default.
• W2588681701 hasConceptScore W2588681701C142052008 @default.
• W2588681701 hasConceptScore W2588681701C142724271 @default.
• W2588681701 hasConceptScore W2588681701C156957248 @default.
• W2588681701 hasConceptScore W2588681701C185032368 @default.
• W2588681701 hasConceptScore W2588681701C203014093 @default.
• W2588681701 hasConceptScore W2588681701C2776301714 @default.
• W2588681701 hasConceptScore W2588681701C2776940978 @default.
• W2588681701 hasConceptScore W2588681701C2779740938 @default.
• W2588681701 hasConceptScore W2588681701C2781069245 @default.
• W2588681701 hasConceptScore W2588681701C3013748606 @default.
• W2588681701 hasConceptScore W2588681701C71924100 @default.
• W2588681701 hasConceptScore W2588681701C90924648 @default.
• W2588681701 hasFunder F4320338462 @default.

• next