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• W2588720459 abstract "A new test of peripheral color contrast is described. A high-definition color monitor driven by a personal computer with a graphics interface card displays an annulus subtending 25° at the eye. The color contrast between the annulus and the background can be varied. Forty-five degrees of the annulus is randomly removed in one of four quadrants. Patients are asked to identify the position of the gap while fixating a central spot. The minimum color contrast between annulus and background at which the identification is possible is between 13-16% for the protan, deuteran, and tritan axis in normal subjects. This threshold value changes little with age, refractive error, or pupillary aperture, and test-retest variability is low. Testing one eye takes only 1-2 min. The test was applied to ocular-hypertensive and glaucomatous patients. All patients with glaucoma had thresholds greater than two standard deviations (SD) above the normal mean. In addition, 97% of glaucoma patients had thresholds greater than four SDs, and 95% had thresholds more than five SDs above the normal mean. Most patients with ocular hypertension and clinical signs indicating a low or medium risk of conversion to glaucoma had thresholds under the upper limit of normal. High-risk patients with ocular hypertension fell into two groups. One approximated to normal; the other had elevated thresholds, which in many cases were more than four SDs above the normal mean. The epidemiologic consequences of this test are discussed. Invest Ophthalmol Vis Sci 32:2779-2789, 1991 Arden and Jacobson 1 described a method of measuring contrast sensitivity to black and white gratings and showed losses at low spatial frequencies in patients with glaucoma and ocular hypertension. They suggested that this test would permit mass screening. However, this was hopelessly optimistic; the upper limit of normal overlapped values obtained from glaucomatous patients with the best preserved vision. Improved techniques, in which the grating was temporally and spatially modulated improved discrimination, 2 but the incidence of false-positive and false-negative results was unacceptably high. Thus, although many authors agree that losses of contrast sensitivity" @default.
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• W2588720459 title "A New Screening Test for Preglaucomarous Visual Loss" @default.
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