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• W2588895069 abstract "A convenient synthesis of substituted spiroindenoquinoxalines at mild and green conditions was developed. Multicomponent reaction of substituted phenylene diamines, ninhydrin, malononitrile and N,N'-substituted-2-nitroethene-1,1-diamines produced the target compounds. Twelve new spiroindenoquinoxalines were obtained, and their ability in inhibition of acetyl and butyrylcholinesterases were investigated both in vitro and in silico. All compounds showed moderate level activity against both acetyl and butyrylcholinesterases." @default.
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• W2588895069 date "2017-04-01" @default.
• W2588895069 modified "2023-10-06" @default.
• W2588895069 title "Green synthesis of novel spiro-indenoquinoxaline derivatives and their cholinesterases inhibition activity" @default.
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• W2588895069 doi "https://doi.org/10.1016/j.bmc.2017.02.017" @default.
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