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- W2589274998 abstract "Bovine herpesvirus (BoHV) type 1 is an important agricultural pathogen that infects cattle and other ruminants worldwide. Acute infection of the oro-respiratory tract leads to immune suppression and allows commensal bacteria to infect an otherwise healthy lower respiratory tract. This condition is known as the Bovine Respiratory Disease (BRD). BoHV-1 latently infects the host for life and periodical stress events re-initiate BRD, translating into high morbidity and large economic losses. To gain a better understanding of the biology of BoHV-1 and the disease it causes, we elucidated the protein composition of extracellular virions using liquid chromatography-mass spectrometry analysis. We detected 33 viral proteins, including the expected proteins of the nucleocapsid and envelope as well as other regulatory proteins present in the viral tegument. In addition to viral proteins, we have also identified packaged proteins of host origin. This constitutes the first proteomic characterization of the BoHV virion." @default.
- W2589274998 created "2017-03-03" @default.
- W2589274998 creator A5001223477 @default.
- W2589274998 creator A5012907839 @default.
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- W2589274998 creator A5060469989 @default.
- W2589274998 creator A5081746369 @default.
- W2589274998 creator A5088443358 @default.
- W2589274998 date "2017-02-20" @default.
- W2589274998 modified "2023-09-23" @default.
- W2589274998 title "Protein Composition of the Bovine Herpesvirus 1.1 Virion" @default.
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