FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2589337515> ?p ?o ?g. }

• W2589337515 endingPage "368" @default.
• W2589337515 startingPage "368" @default.
• W2589337515 abstract "368 Background: The management of testicular seminoma (TS) is evolving with guidelines supporting differential use of chemotherapy (CT) and radiotherapy (RT) depending on stage and presentation. We examined modern practice patterns in TS using the National Cancer Data Base. Methods: Data on 41,745 patients with TS treated between 1998 and 2010 were analyzed. Patients were grouped by stage based on National Comprehensive Cancer Network treatment guidelines. Multivariate generalized estimating equation models were used to assess factors associated with treatment paradigms. Results: Rates of surveillance after orchiectomy for those with stage IA/B TS increased from 21.4% during 1998-2001 to 40.4% from 2006-2010. Despite this, RT remained the most common adjuvant therapy (47.9% in 2006-2010). Use of adjuvant CT increased from 1.7% to 10.6% during this time. Patients with stage IS TS most commonly received RT; however, in 2006-2010, 32.4% of patients received surveillance and 15.6% received CT. Receipt of surveillance for those with stage IIA/B TS remained flat at ~12% while the use of CT rose (34.4% in 2006-2010 vs. 22.5% in 1998-2001). For patients with stage IA/B TS, Medicare or uninsured patients were more likely to receive surveillance vs. CT/RT (OR 1.54, p<0.0001 and OR 1.26, p<0.0001 respectively). Adjuvant CT/RT was more common at high volume centers (OR 0.63 vs. low volume, p<0.0001) and in patients with larger tumors (OR 0.80 for tumors ≥ 4 cm, p<0.0001). Among patients with stage IA/B TS who received adjuvant RT/CT, Medicaid or uninsured patients (OR 0.55, p<0.0001 and OR 0.68, p<0.0001 respectively) and those treated at NCI network cancer centers (OR 0.40 vs. community centers, p<0.0001) were less likely to receive RT vs. CT. For stage IIA/B TS patients, facility type was the strongest predictor for the receipt of RT vs. CT (OR 0.54 at NCI network centers, p<0.0001). Conclusions: Management of TS appears at least partially driven by economic concerns and facility type, especially in regards to selection of stage I patients for surveillance, the preferred management for this group. Many patients with stage IS are not managed according to published guidelines. Action is needed to ensure all patients with TS receive guideline supported care." @default.
• W2589337515 created "2017-03-03" @default.
• W2589337515 creator A5009198168 @default.
• W2589337515 creator A5028786045 @default.
• W2589337515 creator A5043585838 @default.
• W2589337515 creator A5048513152 @default.
• W2589337515 creator A5085626001 @default.
• W2589337515 date "2014-02-01" @default.
• W2589337515 modified "2023-10-18" @default.
• W2589337515 title "Modern patterns of care in testicular seminoma: Results from the National Cancer database." @default.
• W2589337515 doi "https://doi.org/10.1200/jco.2014.32.4_suppl.368" @default.
• W2589337515 hasPublicationYear "2014" @default.
• W2589337515 type Work @default.
• W2589337515 sameAs 2589337515 @default.
• W2589337515 citedByCount "0" @default.
• W2589337515 crossrefType "journal-article" @default.
• W2589337515 hasAuthorship W2589337515A5009198168 @default.
• W2589337515 hasAuthorship W2589337515A5028786045 @default.
• W2589337515 hasAuthorship W2589337515A5043585838 @default.
• W2589337515 hasAuthorship W2589337515A5048513152 @default.
• W2589337515 hasAuthorship W2589337515A5085626001 @default.
• W2589337515 hasConcept C121608353 @default.
• W2589337515 hasConcept C126322002 @default.
• W2589337515 hasConcept C126894567 @default.
• W2589337515 hasConcept C141071460 @default.
• W2589337515 hasConcept C146357865 @default.
• W2589337515 hasConcept C151730666 @default.
• W2589337515 hasConcept C2776212926 @default.
• W2589337515 hasConcept C2776694085 @default.
• W2589337515 hasConcept C2778074268 @default.
• W2589337515 hasConcept C2781440318 @default.
• W2589337515 hasConcept C3018227240 @default.
• W2589337515 hasConcept C38180746 @default.
• W2589337515 hasConcept C509974204 @default.
• W2589337515 hasConcept C530470458 @default.
• W2589337515 hasConcept C71924100 @default.
• W2589337515 hasConcept C86803240 @default.
• W2589337515 hasConceptScore W2589337515C121608353 @default.
• W2589337515 hasConceptScore W2589337515C126322002 @default.
• W2589337515 hasConceptScore W2589337515C126894567 @default.
• W2589337515 hasConceptScore W2589337515C141071460 @default.
• W2589337515 hasConceptScore W2589337515C146357865 @default.
• W2589337515 hasConceptScore W2589337515C151730666 @default.
• W2589337515 hasConceptScore W2589337515C2776212926 @default.
• W2589337515 hasConceptScore W2589337515C2776694085 @default.
• W2589337515 hasConceptScore W2589337515C2778074268 @default.
• W2589337515 hasConceptScore W2589337515C2781440318 @default.
• W2589337515 hasConceptScore W2589337515C3018227240 @default.
• W2589337515 hasConceptScore W2589337515C38180746 @default.
• W2589337515 hasConceptScore W2589337515C509974204 @default.
• W2589337515 hasConceptScore W2589337515C530470458 @default.
• W2589337515 hasConceptScore W2589337515C71924100 @default.
• W2589337515 hasConceptScore W2589337515C86803240 @default.
• W2589337515 hasIssue "4_suppl" @default.
• W2589337515 hasLocation W25893375151 @default.
• W2589337515 hasOpenAccess W2589337515 @default.
• W2589337515 hasPrimaryLocation W25893375151 @default.
• W2589337515 hasRelatedWork W1535958986 @default.
• W2589337515 hasRelatedWork W2105314330 @default.
• W2589337515 hasRelatedWork W2145575862 @default.
• W2589337515 hasRelatedWork W2383214251 @default.
• W2589337515 hasRelatedWork W2410996996 @default.
• W2589337515 hasRelatedWork W2427200476 @default.
• W2589337515 hasRelatedWork W2428855231 @default.
• W2589337515 hasRelatedWork W2432246021 @default.
• W2589337515 hasRelatedWork W3030381566 @default.
• W2589337515 hasRelatedWork W3130060490 @default.
• W2589337515 hasVolume "32" @default.
• W2589337515 isParatext "false" @default.
• W2589337515 isRetracted "false" @default.
• W2589337515 magId "2589337515" @default.
• W2589337515 workType "article" @default.