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- W2589713426 abstract "OBJECTIVE: To determine the relationship between cognitive measures and gait and balance performance in Parkinson9s disease (PD). BACKGROUND: It is known that cognitive function, especially executive function and attention play a role in gait and falls. However, it is not known how cognitive impairments relate to objective measures of balance and gait in neurological disorders such as PD. The purpose of this study was to better delineate this relationship. DESIGN/METHODS: This is a cross sectional study using baseline data from a vitamin D intervention study. Nineteen participants with a mean PD duration of 9.5 years (SD+5.9) underwent cognitive, gait, and balance testing in the “on” state. All testing was completed within a one-month time window. Pearson correlations were used to correlate gait and balance measures and cognitive test performance. Gait was measured with an instrumented Timed Up and Go (iTUG) test from APDM and balance with a Sensory Organization Test (SOT) and Motor Control Test (MCT) to backwards and forwards perturbations from Neurocom Equitest. Cognitive measures included tests of global function (MOCA), memory (WMS-III Logical Memory), executive (trails A & B, Stroop, WAIS-III letter-number sequencing, digit symbol), visual spatial (JoLo), attention (Stroop, WAIS-R digit span forwards and backwards), and language (Boston naming, verbal fluency f9s, animals, vegetables). RESULTS: The most consistent correlations were between measures of executive function and gait and balance. Trails A correlated with stride velocity (p=0.01); Trails B with equilibrium score in condition 5 of the SOT (p= CONCLUSIONS: Our data supports the relationship between objective gait and balance measures and cognitive function, specifically executive function in patients with PD. Supported by: Department of Veteran9s Affairs UPSHS grant NS38175 and the Oregon Clinical and Translation Research Institute (OCTRI), grant number UL1 RR024140 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH). Disclosure: Dr. Peterson has nothing to disclose. Dr. Lobb has nothing to disclose. Dr. Mancini has nothing to disclose. Dr. Horak has received personal compensation for activities with Consensus Medical and North American Education and APDM. Dr. Horak has received personal compensation in an editorial capacity for Gait and Posture." @default.
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- W2589713426 date "2013-02-12" @default.
- W2589713426 modified "2023-09-23" @default.
- W2589713426 title "The Relationship between Cognitive Testing and Gait and Balance Measures in Parkinson's Disease (P04.169)" @default.
- W2589713426 hasPublicationYear "2013" @default.
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