FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2589735890> ?p ?o ?g. }

• W2589735890 endingPage "1126" @default.
• W2589735890 startingPage "1116" @default.
• W2589735890 abstract "Aims To compare glucose control and safety of different basal insulin therapies ( BI , including I nsulin NPH , glargine and detemir) in real‐world clinical settings based on a large‐scale registry study. Methods In this multi‐center 6‐month prospective observational study, patients with type 2 diabetes ( HbA1c ≥ 7%) who were uncontrolled by oral anti‐diabetic drugs ( OADs ) and were willing to initiate BI therapy were enrolled from 209 hospitals within 8 regions of C hina. Type and dose of BI were at the physician's discretion and the patients’ willingness. Interviews were conducted at 0 months (visit 1), 3 months (visit 2) and 6 months (visit 3). Outcomes included change in HbA1c , hypoglycemia rate and body weight from baseline at 6 months. Results A total of 16 341 and 9002 subjects were involved in I ntention‐ T o‐ T reat ( ITT ) and per‐protocol ( PP ) analysis, respectively. After PS regression adjustment, ITT analysis showed that reduction in HbA1c in glargine (2.2% ± 2.1%) and detemir groups (2.2% ± 2.1%) was higher than that in the NPH group (2.0% ± 2.2%) ( P < .01). The detemir group had the lowest weight gain (−0.1 ± 2.9 kg) compared with the glargine (+0.1 ± 3.0 kg) and NPH (+0.3 ± 3.1 kg) groups ( P < .05). The glargine group had the lowest rate of minor hypoglycaemia, while there was no difference in severe hypoglycaemia among the 3 groups. The results observed in PP analyses were consistent with those in ITT analysis. Conclusion In a real‐world clinical setting in C hina, treatment with long‐acting insulin analogues was associated with better glycaemic control, as well as less hypoglycaemia and weight gain than treatment with NPH insulin in type 2 diabetes patients. However, the clinical relevance of these observations must be interpreted with caution." @default.
• W2589735890 created "2017-03-03" @default.
• W2589735890 creator A5007251193 @default.
• W2589735890 creator A5008962800 @default.
• W2589735890 creator A5011196998 @default.
• W2589735890 creator A5012775407 @default.
• W2589735890 creator A5012857374 @default.
• W2589735890 creator A5026230555 @default.
• W2589735890 creator A5027624056 @default.
• W2589735890 creator A5033041702 @default.
• W2589735890 creator A5037456730 @default.
• W2589735890 creator A5051159076 @default.
• W2589735890 creator A5058358879 @default.
• W2589735890 creator A5058514032 @default.
• W2589735890 creator A5058666299 @default.
• W2589735890 creator A5075417158 @default.
• W2589735890 creator A5078369871 @default.
• W2589735890 creator A5083581289 @default.
• W2589735890 creator A5086470039 @default.
• W2589735890 date "2017-04-03" @default.
• W2589735890 modified "2023-10-14" @default.
• W2589735890 title "Comparative effectiveness and safety of different basal insulins in a real-world setting" @default.
• W2589735890 cites W1587185600 @default.
• W2589735890 cites W1764970215 @default.
• W2589735890 cites W1878621938 @default.
• W2589735890 cites W1912785425 @default.
• W2589735890 cites W1953393606 @default.
• W2589735890 cites W1971556813 @default.
• W2589735890 cites W1980795994 @default.
• W2589735890 cites W1982977614 @default.
• W2589735890 cites W1987714540 @default.
• W2589735890 cites W1987854488 @default.
• W2589735890 cites W2001385630 @default.
• W2589735890 cites W2009682614 @default.
• W2589735890 cites W2012125528 @default.
• W2589735890 cites W2016846562 @default.
• W2589735890 cites W2057595002 @default.
• W2589735890 cites W2064790183 @default.
• W2589735890 cites W2065330837 @default.
• W2589735890 cites W2090244618 @default.
• W2589735890 cites W2096896128 @default.
• W2589735890 cites W2103231672 @default.
• W2589735890 cites W2109416725 @default.
• W2589735890 cites W2118032584 @default.
• W2589735890 cites W2126781806 @default.
• W2589735890 cites W2127521907 @default.
• W2589735890 cites W2143943492 @default.
• W2589735890 cites W2149265991 @default.
• W2589735890 cites W2156599045 @default.
• W2589735890 cites W2319588407 @default.
• W2589735890 cites W2473954980 @default.
• W2589735890 cites W2527670279 @default.
• W2589735890 cites W2573858888 @default.
• W2589735890 cites W4214683493 @default.
• W2589735890 cites W66041704 @default.
• W2589735890 doi "https://doi.org/10.1111/dom.12920" @default.
• W2589735890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28230322" @default.
• W2589735890 hasPublicationYear "2017" @default.
• W2589735890 type Work @default.
• W2589735890 sameAs 2589735890 @default.
• W2589735890 citedByCount "11" @default.
• W2589735890 countsByYear W25897358902017 @default.
• W2589735890 countsByYear W25897358902018 @default.
• W2589735890 countsByYear W25897358902019 @default.
• W2589735890 countsByYear W25897358902020 @default.
• W2589735890 countsByYear W25897358902022 @default.
• W2589735890 countsByYear W25897358902023 @default.
• W2589735890 crossrefType "journal-article" @default.
• W2589735890 hasAuthorship W2589735890A5007251193 @default.
• W2589735890 hasAuthorship W2589735890A5008962800 @default.
• W2589735890 hasAuthorship W2589735890A5011196998 @default.
• W2589735890 hasAuthorship W2589735890A5012775407 @default.
• W2589735890 hasAuthorship W2589735890A5012857374 @default.
• W2589735890 hasAuthorship W2589735890A5026230555 @default.
• W2589735890 hasAuthorship W2589735890A5027624056 @default.
• W2589735890 hasAuthorship W2589735890A5033041702 @default.
• W2589735890 hasAuthorship W2589735890A5037456730 @default.
• W2589735890 hasAuthorship W2589735890A5051159076 @default.
• W2589735890 hasAuthorship W2589735890A5058358879 @default.
• W2589735890 hasAuthorship W2589735890A5058514032 @default.
• W2589735890 hasAuthorship W2589735890A5058666299 @default.
• W2589735890 hasAuthorship W2589735890A5075417158 @default.
• W2589735890 hasAuthorship W2589735890A5078369871 @default.
• W2589735890 hasAuthorship W2589735890A5083581289 @default.
• W2589735890 hasAuthorship W2589735890A5086470039 @default.
• W2589735890 hasBestOaLocation W25897358902 @default.
• W2589735890 hasConcept C126322002 @default.
• W2589735890 hasConcept C134018914 @default.
• W2589735890 hasConcept C187212893 @default.
• W2589735890 hasConcept C23131810 @default.
• W2589735890 hasConcept C2777180221 @default.
• W2589735890 hasConcept C2778024521 @default.
• W2589735890 hasConcept C2779306644 @default.
• W2589735890 hasConcept C2779920387 @default.
• W2589735890 hasConcept C2780668416 @default.
• W2589735890 hasConcept C555293320 @default.
• W2589735890 hasConcept C71924100 @default.
• W2589735890 hasConceptScore W2589735890C126322002 @default.

• next