FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2589778060> ?p ?o ?g. }

• W2589778060 abstract "Abstract Biochemical adaptation is one of the basic functions that are widely implemented in biological systems for a variety of purposes such as signal sensing, stress response and homeostasis. The adaptation time scales span from milliseconds to days, involving different regulatory machineries in different processes. The adaptive networks with enzymatic regulation (ERNs) have been investigated in detail. But it remains unclear if and how other forms of regulation will impact the network topology and other features of the function. Here, we systematically studied three-node transcriptional regulatory networks (TRNs), with three different types of gene regulation logics. We found that the topologies of adaptive gene regulatory networks can still be grouped into two general classes: negative feedback loop (NFBL) and incoherent feed-forward loop (IFFL), but with some distinct topological features comparing to the enzymatic networks. Specifically, an auto-activation loop on the buffer node is necessary for the NFBL class. For IFFL class, the control node can be either a proportional node or an inversely-proportional node. Furthermore, the tunability of adaptive behavior differs between TRNs and ERNs. Our findings highlight the role of regulation forms in network topology, implementation and dynamics." @default.
• W2589778060 created "2017-03-03" @default.
• W2589778060 creator A5002919496 @default.
• W2589778060 creator A5010671008 @default.
• W2589778060 creator A5042947805 @default.
• W2589778060 creator A5054567270 @default.
• W2589778060 creator A5077680938 @default.
• W2589778060 date "2017-02-24" @default.
• W2589778060 modified "2023-10-02" @default.
• W2589778060 title "Adaptation with transcriptional regulation" @default.
• W2589778060 cites W1645305843 @default.
• W2589778060 cites W1970070519 @default.
• W2589778060 cites W1975351609 @default.
• W2589778060 cites W1981047637 @default.
• W2589778060 cites W1987315263 @default.
• W2589778060 cites W1997051196 @default.
• W2589778060 cites W1997443428 @default.
• W2589778060 cites W2002189052 @default.
• W2589778060 cites W2003155571 @default.
• W2589778060 cites W2022891974 @default.
• W2589778060 cites W2028979517 @default.
• W2589778060 cites W2030945597 @default.
• W2589778060 cites W2038087154 @default.
• W2589778060 cites W2039806374 @default.
• W2589778060 cites W2046355391 @default.
• W2589778060 cites W2051497876 @default.
• W2589778060 cites W2057686341 @default.
• W2589778060 cites W2072159031 @default.
• W2589778060 cites W2079588007 @default.
• W2589778060 cites W2098199730 @default.
• W2589778060 cites W2100790213 @default.
• W2589778060 cites W2102616699 @default.
• W2589778060 cites W2103331163 @default.
• W2589778060 cites W2111759547 @default.
• W2589778060 cites W2113405823 @default.
• W2589778060 cites W2117056464 @default.
• W2589778060 cites W2123880844 @default.
• W2589778060 cites W2123973944 @default.
• W2589778060 cites W2126602684 @default.
• W2589778060 cites W2132507158 @default.
• W2589778060 cites W2132926156 @default.
• W2589778060 cites W2133403209 @default.
• W2589778060 cites W2134759932 @default.
• W2589778060 cites W2135879265 @default.
• W2589778060 cites W2137244527 @default.
• W2589778060 cites W2144347639 @default.
• W2589778060 cites W2157737080 @default.
• W2589778060 cites W2162647894 @default.
• W2589778060 cites W2257267783 @default.
• W2589778060 cites W2517592377 @default.
• W2589778060 cites W791986181 @default.
• W2589778060 doi "https://doi.org/10.1038/srep42648" @default.
• W2589778060 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5324054" @default.
• W2589778060 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28233824" @default.
• W2589778060 hasPublicationYear "2017" @default.
• W2589778060 type Work @default.
• W2589778060 sameAs 2589778060 @default.
• W2589778060 citedByCount "25" @default.
• W2589778060 countsByYear W25897780602018 @default.
• W2589778060 countsByYear W25897780602019 @default.
• W2589778060 countsByYear W25897780602020 @default.
• W2589778060 countsByYear W25897780602021 @default.
• W2589778060 countsByYear W25897780602022 @default.
• W2589778060 countsByYear W25897780602023 @default.
• W2589778060 crossrefType "journal-article" @default.
• W2589778060 hasAuthorship W2589778060A5002919496 @default.
• W2589778060 hasAuthorship W2589778060A5010671008 @default.
• W2589778060 hasAuthorship W2589778060A5042947805 @default.
• W2589778060 hasAuthorship W2589778060A5054567270 @default.
• W2589778060 hasAuthorship W2589778060A5077680938 @default.
• W2589778060 hasBestOaLocation W25897780601 @default.
• W2589778060 hasConcept C104317684 @default.
• W2589778060 hasConcept C114614502 @default.
• W2589778060 hasConcept C121332964 @default.
• W2589778060 hasConcept C139807058 @default.
• W2589778060 hasConcept C14036430 @default.
• W2589778060 hasConcept C150194340 @default.
• W2589778060 hasConcept C152662350 @default.
• W2589778060 hasConcept C154945302 @default.
• W2589778060 hasConcept C165801399 @default.
• W2589778060 hasConcept C165864922 @default.
• W2589778060 hasConcept C169760540 @default.
• W2589778060 hasConcept C184720557 @default.
• W2589778060 hasConcept C186886427 @default.
• W2589778060 hasConcept C199845137 @default.
• W2589778060 hasConcept C27153228 @default.
• W2589778060 hasConcept C2777212361 @default.
• W2589778060 hasConcept C28225019 @default.
• W2589778060 hasConcept C31258907 @default.
• W2589778060 hasConcept C33923547 @default.
• W2589778060 hasConcept C38652104 @default.
• W2589778060 hasConcept C41008148 @default.
• W2589778060 hasConcept C54355233 @default.
• W2589778060 hasConcept C62520636 @default.
• W2589778060 hasConcept C62611344 @default.
• W2589778060 hasConcept C67339327 @default.
• W2589778060 hasConcept C6929976 @default.
• W2589778060 hasConcept C70721500 @default.
• W2589778060 hasConcept C86803240 @default.
• W2589778060 hasConcept C93586867 @default.

• next