FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2589992899> ?p ?o ?g. }

• W2589992899 endingPage "368" @default.
• W2589992899 startingPage "368" @default.
• W2589992899 abstract "368 Background: Appendiceal neoplasms are poorly understood and represent less than 0.5% of all gastrointestinal cancers. We describe the presentation, pathologic characteristics, and treatment interventions that may have affected patient (pt) outcome. Methods: This is a retrospective review of pts with appendiceal neoplasms treated at NYU Medical Center and/or NYU Cancer Center between 2002-2011. Pt demographics and medical history were collected, including pathology reports, operative findings, imaging studies, treatment and outcomes. Results: 41 consecutive pts with varying stages of appendiceal cancer were identified (70.7% female, median age 57). Most common presentations included: 15 (36.6%) gynecologic complaints, 12 (29.2%) acute appendicitis, and 11 (26.8%) abdominal symptoms. Histologic subtypes were 27 (65.9%) mucinous cystadenomas and 14 (34.1%) adenocarcinomas of which 12 (29.3%) were mucinous adenocarcinoma and 2 (4.9%) were signet cell mucinous adenocarcinoma. Distribution of stages was: 27 (65.9%) stage 0, 2 (4.9%) stage I, 2 (4.9%) stage IIA/B, 6 (14.6%) stage IVA, and 4 (9.8%) stage IVB. All pts underwent one or more of the following procedures: appendectomy (n=39), colectomy (n=9), bilateral salpingo-oophorectomy (n=4), other (n=1). 9 of 10 stage IV pts underwent debulking, of those 2 had suboptimal debulking. 1 stage II pt and 4 stage IV pts (all mucinous adenocarcinoma subtype) received hyperthermic intraperitoneal chemotherapy (HIPEC) with mitomycin-C (all female, median age 39). In contrast, 6 stage IV pts (2 signet cell adenocarcinoma, 4 mucinous adenocarcinoma subtypes) did not receive HIPEC (67% female, median age 80). 1 pt received systemic 5FU based chemotherapy in addition to HIPEC (female, age 39). Median overall survival (mOS) for all pts ≥ stage II is 32 months. mOS in pts ≥ stage II who did not receive HIPEC is 8 mo whereas mOS in pts ≥ stage II who received HIPEC has not been reached. Conclusions: Appendiceal cancer is frequently detected as an incidental finding for gynecologic and abdominal complaints or presents as acute appendicitis. Surgery is the mainstay of treatment for this disease. Additional therapy including HIPEC may be of benefit in select advanced stage patients." @default.
• W2589992899 created "2017-03-03" @default.
• W2589992899 creator A5008605488 @default.
• W2589992899 creator A5009920091 @default.
• W2589992899 creator A5030565266 @default.
• W2589992899 creator A5048973199 @default.
• W2589992899 date "2013-02-01" @default.
• W2589992899 modified "2023-09-25" @default.
• W2589992899 title "Mucinous neoplasms of the appendix: A single-center experience." @default.
• W2589992899 doi "https://doi.org/10.1200/jco.2013.31.4_suppl.368" @default.
• W2589992899 hasPublicationYear "2013" @default.
• W2589992899 type Work @default.
• W2589992899 sameAs 2589992899 @default.
• W2589992899 citedByCount "0" @default.
• W2589992899 crossrefType "journal-article" @default.
• W2589992899 hasAuthorship W2589992899A5008605488 @default.
• W2589992899 hasAuthorship W2589992899A5009920091 @default.
• W2589992899 hasAuthorship W2589992899A5030565266 @default.
• W2589992899 hasAuthorship W2589992899A5048973199 @default.
• W2589992899 hasConcept C121608353 @default.
• W2589992899 hasConcept C126322002 @default.
• W2589992899 hasConcept C141071460 @default.
• W2589992899 hasConcept C146357865 @default.
• W2589992899 hasConcept C151730666 @default.
• W2589992899 hasConcept C2776364125 @default.
• W2589992899 hasConcept C2780427987 @default.
• W2589992899 hasConcept C2780898957 @default.
• W2589992899 hasConcept C2781100745 @default.
• W2589992899 hasConcept C2781182431 @default.
• W2589992899 hasConcept C71924100 @default.
• W2589992899 hasConcept C86803240 @default.
• W2589992899 hasConceptScore W2589992899C121608353 @default.
• W2589992899 hasConceptScore W2589992899C126322002 @default.
• W2589992899 hasConceptScore W2589992899C141071460 @default.
• W2589992899 hasConceptScore W2589992899C146357865 @default.
• W2589992899 hasConceptScore W2589992899C151730666 @default.
• W2589992899 hasConceptScore W2589992899C2776364125 @default.
• W2589992899 hasConceptScore W2589992899C2780427987 @default.
• W2589992899 hasConceptScore W2589992899C2780898957 @default.
• W2589992899 hasConceptScore W2589992899C2781100745 @default.
• W2589992899 hasConceptScore W2589992899C2781182431 @default.
• W2589992899 hasConceptScore W2589992899C71924100 @default.
• W2589992899 hasConceptScore W2589992899C86803240 @default.
• W2589992899 hasIssue "4_suppl" @default.
• W2589992899 hasLocation W25899928991 @default.
• W2589992899 hasOpenAccess W2589992899 @default.
• W2589992899 hasPrimaryLocation W25899928991 @default.
• W2589992899 hasRelatedWork W1015267879 @default.
• W2589992899 hasRelatedWork W165280362 @default.
• W2589992899 hasRelatedWork W1736585674 @default.
• W2589992899 hasRelatedWork W1995975939 @default.
• W2589992899 hasRelatedWork W2072520196 @default.
• W2589992899 hasRelatedWork W2239440607 @default.
• W2589992899 hasRelatedWork W2401942322 @default.
• W2589992899 hasRelatedWork W2438943298 @default.
• W2589992899 hasRelatedWork W2622859557 @default.
• W2589992899 hasRelatedWork W4239361744 @default.
• W2589992899 hasVolume "31" @default.
• W2589992899 isParatext "false" @default.
• W2589992899 isRetracted "false" @default.
• W2589992899 magId "2589992899" @default.
• W2589992899 workType "article" @default.