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- W2590092017 abstract "Invasive aspergillosis (IA) is one of the most difficult to treat and, consequently, one of the most lethal fungal infections known to man. Continued use of immunosuppressive agents during chemotherapy and organ transplantation often leads to the development of neutropenia, the primary risk factor for IA. However, IA is also becoming more appreciated in chronic diseases associated with corticosteroid therapy. The innate immune response to Aspergillus fumigatus, the primary agent in IA, plays a pivotal role in the recognition and elimination of organisms from the pulmonary system. This review highlights recent findings about innate host defense mechanisms, including novel aspects of innate cellular immunity and pathogen recognition, and the inflammatory mediators that control infection with A. fumigatus." @default.
- W2590092017 created "2017-03-03" @default.
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- W2590092017 creator A5091669686 @default.
- W2590092017 date "2017-01-01" @default.
- W2590092017 modified "2023-09-27" @default.
- W2590092017 title "Innate Lung Defense during Invasive Aspergillosis: New Mechanisms" @default.
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- W2590092017 doi "https://doi.org/10.1159/000455125" @default.
- W2590092017 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5475230" @default.
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