FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2590157041> ?p ?o ?g. }

• W2590157041 endingPage "10" @default.
• W2590157041 startingPage "1" @default.
• W2590157041 abstract "Purpose. This study aimed to evaluate the effect of chronic treatment with chaetomellic acid A (CAA) on oxidative stress and renal function in a model of renal mass reduction. Methods . Male Wistar rats were subjected to 5/6 nephrectomy (RMR) or sham-operated (SO). One week after surgery, rats have been divided into four experimental groups: RMR: RMR rats without treatment<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mo stretchy=false>(</mml:mo><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle=italic>14</mml:mn><mml:mo stretchy=false>)</mml:mo></mml:math>; RMR + CAA: RMR rats treated with CAA<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mo stretchy=false>(</mml:mo><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle=italic>13</mml:mn><mml:mo stretchy=false>)</mml:mo></mml:math>; SO: SO rats without treatment<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mo stretchy=false>(</mml:mo><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle=italic>13</mml:mn><mml:mo stretchy=false>)</mml:mo></mml:math>; and SO + CAA: SO rats treated with CAA<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mo stretchy=false>(</mml:mo><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle=italic>13</mml:mn><mml:mo stretchy=false>)</mml:mo></mml:math>. CAA was intraperitoneally administered in a dose of 0.23 µ g/Kg three times a week for six months. Results. RMR was accompanied by a significant reduction in catalase and glutathione reductase (GR) activity<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M5><mml:mo stretchy=false>(</mml:mo><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn fontstyle=italic>0.05</mml:mn><mml:mo stretchy=false>)</mml:mo></mml:math>and a decrease in reduced glutathione (GSH)/oxidized glutathione (GSSG) ratio. CAA administration significantly increased catalase and GR activity<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M6><mml:mo stretchy=false>(</mml:mo><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn fontstyle=italic>0.05</mml:mn><mml:mo stretchy=false>)</mml:mo></mml:math>and increased GSH/GSSG ratio, but no significant difference between the treated and nontreated groups was found in this ratio. No significant differences were found between the RMR groups in any of the parameters of renal function. However, CAA administration slightly improves some parameters of renal function. Conclusions. These data suggest that CAA could attenuate 5/6 RMR-induced oxidative stress." @default.
• W2590157041 created "2017-03-03" @default.
• W2590157041 creator A5017628846 @default.
• W2590157041 creator A5020882173 @default.
• W2590157041 creator A5036548685 @default.
• W2590157041 creator A5040898370 @default.
• W2590157041 creator A5051679014 @default.
• W2590157041 creator A5052493209 @default.
• W2590157041 creator A5081466098 @default.
• W2590157041 date "2017-01-01" @default.
• W2590157041 modified "2023-10-17" @default.
• W2590157041 title "The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction" @default.
• W2590157041 cites W1484076261 @default.
• W2590157041 cites W1506043065 @default.
• W2590157041 cites W1558823847 @default.
• W2590157041 cites W1607745865 @default.
• W2590157041 cites W177483469 @default.
• W2590157041 cites W1905334965 @default.
• W2590157041 cites W1939738994 @default.
• W2590157041 cites W1977120464 @default.
• W2590157041 cites W1996294295 @default.
• W2590157041 cites W1996976658 @default.
• W2590157041 cites W2000995954 @default.
• W2590157041 cites W2004984710 @default.
• W2590157041 cites W2008458654 @default.
• W2590157041 cites W2010265433 @default.
• W2590157041 cites W2011927381 @default.
• W2590157041 cites W2018901137 @default.
• W2590157041 cites W2022685972 @default.
• W2590157041 cites W2024402396 @default.
• W2590157041 cites W2029220849 @default.
• W2590157041 cites W2033820729 @default.
• W2590157041 cites W2037135703 @default.
• W2590157041 cites W2037841947 @default.
• W2590157041 cites W2043382780 @default.
• W2590157041 cites W2043578693 @default.
• W2590157041 cites W2051151985 @default.
• W2590157041 cites W2054319024 @default.
• W2590157041 cites W2055576290 @default.
• W2590157041 cites W2055918523 @default.
• W2590157041 cites W2056056517 @default.
• W2590157041 cites W2062226211 @default.
• W2590157041 cites W2072569792 @default.
• W2590157041 cites W2078843599 @default.
• W2590157041 cites W2083173658 @default.
• W2590157041 cites W2083575326 @default.
• W2590157041 cites W2085054034 @default.
• W2590157041 cites W2086855940 @default.
• W2590157041 cites W2087789006 @default.
• W2590157041 cites W2095149231 @default.
• W2590157041 cites W2102088119 @default.
• W2590157041 cites W2107751591 @default.
• W2590157041 cites W2110990077 @default.
• W2590157041 cites W2122074407 @default.
• W2590157041 cites W2123193350 @default.
• W2590157041 cites W2125289626 @default.
• W2590157041 cites W2126146739 @default.
• W2590157041 cites W2128411304 @default.
• W2590157041 cites W2135684059 @default.
• W2590157041 cites W2138236943 @default.
• W2590157041 cites W2140041517 @default.
• W2590157041 cites W2147929482 @default.
• W2590157041 cites W2149907341 @default.
• W2590157041 cites W2155328908 @default.
• W2590157041 cites W2155888953 @default.
• W2590157041 cites W2159264172 @default.
• W2590157041 cites W2161488837 @default.
• W2590157041 cites W2162858008 @default.
• W2590157041 doi "https://doi.org/10.1155/2017/5125980" @default.
• W2590157041 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5343227" @default.
• W2590157041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28326323" @default.
• W2590157041 hasPublicationYear "2017" @default.
• W2590157041 type Work @default.
• W2590157041 sameAs 2590157041 @default.
• W2590157041 citedByCount "3" @default.
• W2590157041 countsByYear W25901570412017 @default.
• W2590157041 countsByYear W25901570412020 @default.
• W2590157041 countsByYear W25901570412021 @default.
• W2590157041 crossrefType "journal-article" @default.
• W2590157041 hasAuthorship W2590157041A5017628846 @default.
• W2590157041 hasAuthorship W2590157041A5020882173 @default.
• W2590157041 hasAuthorship W2590157041A5036548685 @default.
• W2590157041 hasAuthorship W2590157041A5040898370 @default.
• W2590157041 hasAuthorship W2590157041A5051679014 @default.
• W2590157041 hasAuthorship W2590157041A5052493209 @default.
• W2590157041 hasAuthorship W2590157041A5081466098 @default.
• W2590157041 hasBestOaLocation W25901570411 @default.
• W2590157041 hasConcept C11413529 @default.
• W2590157041 hasConcept C192562407 @default.
• W2590157041 hasConcept C41008148 @default.
• W2590157041 hasConceptScore W2590157041C11413529 @default.
• W2590157041 hasConceptScore W2590157041C192562407 @default.
• W2590157041 hasConceptScore W2590157041C41008148 @default.
• W2590157041 hasFunder F4320334779 @default.
• W2590157041 hasLocation W25901570411 @default.
• W2590157041 hasLocation W25901570412 @default.
• W2590157041 hasLocation W25901570413 @default.
• W2590157041 hasLocation W25901570414 @default.

• next