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• W2590167411 startingPage "2835" @default.
• W2590167411 abstract "An efficient synthesis of diversified indolizine derivatives was developed via CuBr-catalyzed reaction of pyridines, methyl ketones and alkenoic acids under solvent-free conditions in oxygen atmosphere. This synthesis involves cascade processes of copper-catalyzed bromination of the methyl ketone, 1,3-dipolar cycloaddition of the pyridinium ylide with the alkenoic acid, followed by oxidative decarboxylation and dehydrogenative aromatization of the primary cycloadduct. By this protocol, a wide range of indoliznes with different substitution patterns were selectively prepared in one pot from simple substrates in good to excellent yields." @default.
• W2590167411 created "2017-03-03" @default.
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• W2590167411 date "2017-02-28" @default.
• W2590167411 modified "2023-10-18" @default.
• W2590167411 title "CuBr-Catalyzed Aerobic Decarboxylative Cycloaddition for the Synthesis of Indolizines under Solvent-Free Conditions" @default.
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• W2590167411 doi "https://doi.org/10.1021/acs.joc.6b02455" @default.
• W2590167411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28225279" @default.
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