Matches in SemOpenAlex for { <https://semopenalex.org/work/W2590237305> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2590237305 endingPage "325" @default.
- W2590237305 startingPage "321" @default.
- W2590237305 abstract "Objective To investigate the mechanism of the permeability change in the blood brain barrier(BBB)at early stage of infectious brain edema which was pretreated with LPS.Methods PMNs were isolated and purified.The concentration of Glu was measured in the supernatant without cells.The rat BMECs were primarily isolated and cultured.The permeability of BMECs waB evaluated by measuring the passing rate of 125 I-BSA via γ ray counter.The expression of NMDAR1 on BMECs was evaluated.Results The concentration of Glu in the LPS preconditioning PMNs subgroup at 5 rain time point was highest.In each group conditioned for 240 min,the permeability index of Bake average of the LPS preconditioning PMNs extract group was highest(P＜0.01).The expression of NMDARI increased in the LPS preconditioning PMNs extract group was more than that in other groups.Conclusions The research showed for the first time that the concentration of Glu increased after LPS preconditioning and the Glu excreted by PMNs can promote the permeability of BMECs and change the function of BBB,which possibly may be related the mechanism of NMDAR1 expression increased in BMECs.Key words: Lipepolysaccharides/PD; Neatrophils; Capillary permeability; Endothelial cells" @default.
- W2590237305 created "2017-03-03" @default.
- W2590237305 creator A5016416589 @default.
- W2590237305 creator A5035281096 @default.
- W2590237305 creator A5053317931 @default.
- W2590237305 creator A5068463006 @default.
- W2590237305 creator A5083363534 @default.
- W2590237305 creator A5086362637 @default.
- W2590237305 date "2009-03-10" @default.
- W2590237305 modified "2023-09-23" @default.
- W2590237305 title "The influence of brain microvascular endothelial cells permeability induced by extract of LPS pretreated PMNs" @default.
- W2590237305 doi "https://doi.org/10.3760/cma.j.issn.1008-1372.2009.03.011" @default.
- W2590237305 hasPublicationYear "2009" @default.
- W2590237305 type Work @default.
- W2590237305 sameAs 2590237305 @default.
- W2590237305 citedByCount "0" @default.
- W2590237305 crossrefType "journal-article" @default.
- W2590237305 hasAuthorship W2590237305A5016416589 @default.
- W2590237305 hasAuthorship W2590237305A5035281096 @default.
- W2590237305 hasAuthorship W2590237305A5053317931 @default.
- W2590237305 hasAuthorship W2590237305A5068463006 @default.
- W2590237305 hasAuthorship W2590237305A5083363534 @default.
- W2590237305 hasAuthorship W2590237305A5086362637 @default.
- W2590237305 hasConcept C113045295 @default.
- W2590237305 hasConcept C120882062 @default.
- W2590237305 hasConcept C126322002 @default.
- W2590237305 hasConcept C185592680 @default.
- W2590237305 hasConcept C2778402981 @default.
- W2590237305 hasConcept C2780886150 @default.
- W2590237305 hasConcept C3018611479 @default.
- W2590237305 hasConcept C41625074 @default.
- W2590237305 hasConcept C529278444 @default.
- W2590237305 hasConcept C55493867 @default.
- W2590237305 hasConcept C71924100 @default.
- W2590237305 hasConcept C72859922 @default.
- W2590237305 hasConcept C79879829 @default.
- W2590237305 hasConcept C98274493 @default.
- W2590237305 hasConceptScore W2590237305C113045295 @default.
- W2590237305 hasConceptScore W2590237305C120882062 @default.
- W2590237305 hasConceptScore W2590237305C126322002 @default.
- W2590237305 hasConceptScore W2590237305C185592680 @default.
- W2590237305 hasConceptScore W2590237305C2778402981 @default.
- W2590237305 hasConceptScore W2590237305C2780886150 @default.
- W2590237305 hasConceptScore W2590237305C3018611479 @default.
- W2590237305 hasConceptScore W2590237305C41625074 @default.
- W2590237305 hasConceptScore W2590237305C529278444 @default.
- W2590237305 hasConceptScore W2590237305C55493867 @default.
- W2590237305 hasConceptScore W2590237305C71924100 @default.
- W2590237305 hasConceptScore W2590237305C72859922 @default.
- W2590237305 hasConceptScore W2590237305C79879829 @default.
- W2590237305 hasConceptScore W2590237305C98274493 @default.
- W2590237305 hasIssue "03" @default.
- W2590237305 hasLocation W25902373051 @default.
- W2590237305 hasOpenAccess W2590237305 @default.
- W2590237305 hasPrimaryLocation W25902373051 @default.
- W2590237305 hasRelatedWork W1961642276 @default.
- W2590237305 hasRelatedWork W1970422691 @default.
- W2590237305 hasRelatedWork W1977711910 @default.
- W2590237305 hasRelatedWork W1992584798 @default.
- W2590237305 hasRelatedWork W2036405336 @default.
- W2590237305 hasRelatedWork W2037285462 @default.
- W2590237305 hasRelatedWork W2045390477 @default.
- W2590237305 hasRelatedWork W2070890841 @default.
- W2590237305 hasRelatedWork W2094983779 @default.
- W2590237305 hasRelatedWork W2138529199 @default.
- W2590237305 hasRelatedWork W2332372756 @default.
- W2590237305 hasRelatedWork W2351430973 @default.
- W2590237305 hasRelatedWork W2380998368 @default.
- W2590237305 hasRelatedWork W2383588500 @default.
- W2590237305 hasRelatedWork W2386294164 @default.
- W2590237305 hasRelatedWork W2401478362 @default.
- W2590237305 hasRelatedWork W2403601293 @default.
- W2590237305 hasRelatedWork W2416088809 @default.
- W2590237305 hasRelatedWork W2396674554 @default.
- W2590237305 hasRelatedWork W2584735550 @default.
- W2590237305 hasVolume "11" @default.
- W2590237305 isParatext "false" @default.
- W2590237305 isRetracted "false" @default.
- W2590237305 magId "2590237305" @default.
- W2590237305 workType "article" @default.