FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2590313612> ?p ?o ?g. }

• W2590313612 endingPage "125" @default.
• W2590313612 startingPage "120" @default.
• W2590313612 abstract "OBJECTIVE The Barrow Ruptured Aneurysm Trial (BRAT) is a prospective, randomized trial in which treatment with clipping was compared to treatment with coil embolization. Patients were randomized to treatment on presentation with any nontraumatic subarachnoid hemorrhage (SAH). Because all other randomized trials comparing these 2 types of treatments have been limited to saccular aneurysms, the authors analyzed the current BRAT data for this subgroup of lesions. METHODS The primary BRAT analysis included all sources of SAH: nonaneurysmal lesions; saccular, blister, fusiform, and dissecting aneurysms; and SAHs from an aneurysm associated with either an arteriovenous malformation or a fistula. In this post hoc review, the outcomes for the subgroup of patients with saccular aneurysms were further analyzed by type of treatment. The extent of aneurysm obliteration was adjudicated by an independent neuroradiologist not involved in treatment. RESULTS Of the 471 patients enrolled in the BRAT, 362 (77%) had an SAH from a saccular aneurysm. Patients with saccular aneurysms were assigned equally to the clipping and the coiling cohorts (181 each). In each cohort, 3 patients died before treatment and 178 were treated. Of the 178 clip-assigned patients with saccular aneurysms, 1 (1%) was crossed over to coiling, and 64 (36%) of the 178 coil-assigned patients were crossed over to clipping. There was no statistically significant difference in poor outcome (modified Rankin Scale score > 2) between these 2 treatment arms at any recorded time point during 6 years of follow-up. After the initial hospitalization, 1 of 241 (0.4%) clipped saccular aneurysms and 21 of 115 (18%) coiled saccular aneurysms required retreatment (p < 0.001). At the 6-year follow-up, 95% (95/100) of the clipped aneurysms were completely obliterated, compared with 40% (16/40) of the coiled aneurysms (p < 0.001). There was no difference in morbidity between the 2 treatment groups (p = 0.10). CONCLUSIONS In the subgroup of patients with saccular aneurysms enrolled in the BRAT, there was no significant difference between modified Rankin Scale outcomes at any follow-up time in patients with saccular aneurysms assigned to clipping compared with those assigned to coiling (intent-to-treat analysis). At the 6-year follow-up evaluation, rates of retreatment and complete aneurysm obliteration significantly favored patients who underwent clipping compared with those who underwent coiling. Clinical trial registration no.: NCT01593267 (clinicaltrials.gov)." @default.
• W2590313612 created "2017-03-03" @default.
• W2590313612 creator A5000095034 @default.
• W2590313612 creator A5008718222 @default.
• W2590313612 creator A5014273974 @default.
• W2590313612 creator A5022788776 @default.
• W2590313612 creator A5042955766 @default.
• W2590313612 creator A5044984785 @default.
• W2590313612 creator A5063559952 @default.
• W2590313612 date "2018-01-01" @default.
• W2590313612 modified "2023-10-12" @default.
• W2590313612 title "Analysis of saccular aneurysms in the Barrow Ruptured Aneurysm Trial" @default.
• W2590313612 cites W1967899041 @default.
• W2590313612 cites W2044375065 @default.
• W2590313612 cites W2097729692 @default.
• W2590313612 cites W2108086940 @default.
• W2590313612 cites W2108972511 @default.
• W2590313612 cites W2134556305 @default.
• W2590313612 cites W2144792598 @default.
• W2590313612 cites W2166435247 @default.
• W2590313612 cites W2408682253 @default.
• W2590313612 doi "https://doi.org/10.3171/2016.9.jns161301" @default.
• W2590313612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28298031" @default.
• W2590313612 hasPublicationYear "2018" @default.
• W2590313612 type Work @default.
• W2590313612 sameAs 2590313612 @default.
• W2590313612 citedByCount "42" @default.
• W2590313612 countsByYear W25903136122017 @default.
• W2590313612 countsByYear W25903136122018 @default.
• W2590313612 countsByYear W25903136122019 @default.
• W2590313612 countsByYear W25903136122020 @default.
• W2590313612 countsByYear W25903136122021 @default.
• W2590313612 countsByYear W25903136122022 @default.
• W2590313612 countsByYear W25903136122023 @default.
• W2590313612 crossrefType "journal-article" @default.
• W2590313612 hasAuthorship W2590313612A5000095034 @default.
• W2590313612 hasAuthorship W2590313612A5008718222 @default.
• W2590313612 hasAuthorship W2590313612A5014273974 @default.
• W2590313612 hasAuthorship W2590313612A5022788776 @default.
• W2590313612 hasAuthorship W2590313612A5042955766 @default.
• W2590313612 hasAuthorship W2590313612A5044984785 @default.
• W2590313612 hasAuthorship W2590313612A5063559952 @default.
• W2590313612 hasBestOaLocation W25903136121 @default.
• W2590313612 hasConcept C126322002 @default.
• W2590313612 hasConcept C126838900 @default.
• W2590313612 hasConcept C138885662 @default.
• W2590313612 hasConcept C141071460 @default.
• W2590313612 hasConcept C168563851 @default.
• W2590313612 hasConcept C2776035437 @default.
• W2590313612 hasConcept C2776098176 @default.
• W2590313612 hasConcept C2776848632 @default.
• W2590313612 hasConcept C2777736543 @default.
• W2590313612 hasConcept C2779905414 @default.
• W2590313612 hasConcept C2780931571 @default.
• W2590313612 hasConcept C3018386432 @default.
• W2590313612 hasConcept C3020199598 @default.
• W2590313612 hasConcept C41895202 @default.
• W2590313612 hasConcept C541997718 @default.
• W2590313612 hasConcept C71924100 @default.
• W2590313612 hasConceptScore W2590313612C126322002 @default.
• W2590313612 hasConceptScore W2590313612C126838900 @default.
• W2590313612 hasConceptScore W2590313612C138885662 @default.
• W2590313612 hasConceptScore W2590313612C141071460 @default.
• W2590313612 hasConceptScore W2590313612C168563851 @default.
• W2590313612 hasConceptScore W2590313612C2776035437 @default.
• W2590313612 hasConceptScore W2590313612C2776098176 @default.
• W2590313612 hasConceptScore W2590313612C2776848632 @default.
• W2590313612 hasConceptScore W2590313612C2777736543 @default.
• W2590313612 hasConceptScore W2590313612C2779905414 @default.
• W2590313612 hasConceptScore W2590313612C2780931571 @default.
• W2590313612 hasConceptScore W2590313612C3018386432 @default.
• W2590313612 hasConceptScore W2590313612C3020199598 @default.
• W2590313612 hasConceptScore W2590313612C41895202 @default.
• W2590313612 hasConceptScore W2590313612C541997718 @default.
• W2590313612 hasConceptScore W2590313612C71924100 @default.
• W2590313612 hasIssue "1" @default.
• W2590313612 hasLocation W25903136121 @default.
• W2590313612 hasLocation W25903136122 @default.
• W2590313612 hasOpenAccess W2590313612 @default.
• W2590313612 hasPrimaryLocation W25903136121 @default.
• W2590313612 hasRelatedWork W1972894106 @default.
• W2590313612 hasRelatedWork W1999636711 @default.
• W2590313612 hasRelatedWork W2020119635 @default.
• W2590313612 hasRelatedWork W2028838229 @default.
• W2590313612 hasRelatedWork W2045626793 @default.
• W2590313612 hasRelatedWork W2114241827 @default.
• W2590313612 hasRelatedWork W2322567327 @default.
• W2590313612 hasRelatedWork W2476338556 @default.
• W2590313612 hasRelatedWork W292847579 @default.
• W2590313612 hasRelatedWork W4291022083 @default.
• W2590313612 hasVolume "128" @default.
• W2590313612 isParatext "false" @default.
• W2590313612 isRetracted "false" @default.
• W2590313612 magId "2590313612" @default.
• W2590313612 workType "article" @default.