Matches in SemOpenAlex for { <https://semopenalex.org/work/W2590457405> ?p ?o ?g. }
- W2590457405 endingPage "35" @default.
- W2590457405 startingPage "29" @default.
- W2590457405 abstract "This short review focuses on the importance of nonhuman primate nutrition and aging studies and makes the case that a targeted expansion of the use of this highly translatable model would be advantageous to the biology of aging field. First, we describe the high degree of similarity of the model in terms of aging phenotypes including incidence and prevalence of common human age-related diseases. Second, we discuss the importance of the nonhuman primate nutrition and aging studies and the extent to which the outcomes of two ongoing long-term studies of caloric restriction are congruent with short-term equivalent studies in humans. Third, we showcase a number of pharmacological agents previously employed in nonhuman primate studies that display some potential as caloric restriction mimetics. Finally, we present nonhuman primates as an important model for translation of mechanisms of delayed aging identified in studies of shorter-lived animals. Proof of efficacy and safety of candidate longevity agents in nonhuman primates would be a cost-effective means to bring these exciting new avenues a step closer to clinical application." @default.
- W2590457405 created "2017-03-03" @default.
- W2590457405 creator A5059163570 @default.
- W2590457405 creator A5071854848 @default.
- W2590457405 creator A5091189065 @default.
- W2590457405 date "2017-10-01" @default.
- W2590457405 modified "2023-10-17" @default.
- W2590457405 title "Nutrition, metabolism, and targeting aging in nonhuman primates" @default.
- W2590457405 cites W1651161831 @default.
- W2590457405 cites W1794471252 @default.
- W2590457405 cites W1883949114 @default.
- W2590457405 cites W1966132436 @default.
- W2590457405 cites W1970359645 @default.
- W2590457405 cites W1970843424 @default.
- W2590457405 cites W1971817110 @default.
- W2590457405 cites W1972717747 @default.
- W2590457405 cites W1972809276 @default.
- W2590457405 cites W1978161786 @default.
- W2590457405 cites W1980062542 @default.
- W2590457405 cites W1981046818 @default.
- W2590457405 cites W1988210280 @default.
- W2590457405 cites W1989728371 @default.
- W2590457405 cites W1989993058 @default.
- W2590457405 cites W1990620864 @default.
- W2590457405 cites W1991223490 @default.
- W2590457405 cites W1992856669 @default.
- W2590457405 cites W1993132387 @default.
- W2590457405 cites W2001399616 @default.
- W2590457405 cites W2004984537 @default.
- W2590457405 cites W2005517492 @default.
- W2590457405 cites W2007979003 @default.
- W2590457405 cites W2008547497 @default.
- W2590457405 cites W2011657070 @default.
- W2590457405 cites W2011791635 @default.
- W2590457405 cites W2011825776 @default.
- W2590457405 cites W2012399629 @default.
- W2590457405 cites W2014717126 @default.
- W2590457405 cites W2021631452 @default.
- W2590457405 cites W2027927052 @default.
- W2590457405 cites W2030570287 @default.
- W2590457405 cites W2031335227 @default.
- W2590457405 cites W2033694668 @default.
- W2590457405 cites W2045618061 @default.
- W2590457405 cites W2046240999 @default.
- W2590457405 cites W2052749010 @default.
- W2590457405 cites W2052872014 @default.
- W2590457405 cites W2053493267 @default.
- W2590457405 cites W2053510668 @default.
- W2590457405 cites W2054670968 @default.
- W2590457405 cites W2055184550 @default.
- W2590457405 cites W2059465746 @default.
- W2590457405 cites W2063227846 @default.
- W2590457405 cites W2067805867 @default.
- W2590457405 cites W2067957293 @default.
- W2590457405 cites W2068897578 @default.
- W2590457405 cites W2069508648 @default.
- W2590457405 cites W2072712640 @default.
- W2590457405 cites W2073283943 @default.
- W2590457405 cites W2076310317 @default.
- W2590457405 cites W2078991582 @default.
- W2590457405 cites W2082930819 @default.
- W2590457405 cites W2084858824 @default.
- W2590457405 cites W2086888830 @default.
- W2590457405 cites W2094625212 @default.
- W2590457405 cites W2096935190 @default.
- W2590457405 cites W2098343475 @default.
- W2590457405 cites W2100232436 @default.
- W2590457405 cites W2100332091 @default.
- W2590457405 cites W2102749034 @default.
- W2590457405 cites W2103538220 @default.
- W2590457405 cites W2109820081 @default.
- W2590457405 cites W2114489597 @default.
- W2590457405 cites W2117534769 @default.
- W2590457405 cites W2117879192 @default.
- W2590457405 cites W2119117529 @default.
- W2590457405 cites W2119351413 @default.
- W2590457405 cites W2119679507 @default.
- W2590457405 cites W2120112276 @default.
- W2590457405 cites W2121234713 @default.
- W2590457405 cites W2126188293 @default.
- W2590457405 cites W2134191062 @default.
- W2590457405 cites W2134944069 @default.
- W2590457405 cites W2135131246 @default.
- W2590457405 cites W2136829490 @default.
- W2590457405 cites W2138100580 @default.
- W2590457405 cites W2139580438 @default.
- W2590457405 cites W2141314779 @default.
- W2590457405 cites W2142586756 @default.
- W2590457405 cites W2144461742 @default.
- W2590457405 cites W2145044799 @default.
- W2590457405 cites W2148379191 @default.
- W2590457405 cites W2153442288 @default.
- W2590457405 cites W2155782332 @default.
- W2590457405 cites W2156048764 @default.
- W2590457405 cites W2165722123 @default.
- W2590457405 cites W2165852917 @default.
- W2590457405 cites W2172299257 @default.
- W2590457405 cites W2177230473 @default.