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• W2590641123 abstract "DNA chemical modifications regulate genomic function. We present a framework for mapping cytosine and adenosine methylation with the Oxford Nanopore Technologies MinION using this nanopore sequencer's ionic current signal. We map three cytosine variants and two adenine variants. The results show that our model is sensitive enough to detect changes in genomic DNA methylation levels as a function of growth phase in Escherichia coli." @default.
• W2590641123 created "2017-03-03" @default.
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• W2590641123 date "2017-02-20" @default.
• W2590641123 modified "2023-10-06" @default.
• W2590641123 title "Mapping DNA methylation with high-throughput nanopore sequencing" @default.
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• W2590641123 doi "https://doi.org/10.1038/nmeth.4189" @default.
• W2590641123 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5704956" @default.
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