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- W2590974568 abstract "Mitral valve (MV) physiopathological function and the effects of surgical repair can be studied through finite element models (FEMs). However, this approach assumes idealized morphology and boundary conditions limiting the analysis to paradigmatic scenarios and precluding patient-specific surgical planning. To overcome this limitation, we integrated into a MV FEM the patient-specific information about leaflets, annulus and papillary muscles geometry and dynamics, obtained from real-time 3D echocardiography. An ad-hoc web platform was created to facilitate FEM development from remote users, and grant access to parallel computing facilities. This approach was tested simulating MV closure in three normal subjects. Modelled valvular dynamics and quantitative results were consistent with experimental findings from literature. FEMs implementation required about 6 min, while simulations required about 7.5 hours on 32 parallel CPUs. Our approach appears reliable, reproducible and reasonably fast and may constitute the basis for the development of patient-specific tools for MV surgery. Introduction" @default.
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- W2590974568 date "2009-09-20" @default.
- W2590974568 modified "2023-09-26" @default.
- W2590974568 title "Mitral valve patient-specific finite element modeling from 3-D real time echocardiography: a potential new tool for surgical planning" @default.
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