Matches in SemOpenAlex for { <https://semopenalex.org/work/W2590988692> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2590988692 endingPage "296" @default.
- W2590988692 startingPage "293" @default.
- W2590988692 abstract "Objective To investigate the glucose metabolic pattern of brain functional loop in patients with refractory obsessive compulsive disorder (OCD) using 18 F-FDG PET.Methods Eight patients with refractory OCD and 8 age- and gender-matched healthy volunteers underwent 18F-FDG PET brain imaging.SPM software was used for image post-processing and quantitative analysis.Correlation analysis between 18F-FDG uptake and Yale-Brown obsessive compulsive scale(Y-BOCS) score was performed.Results Compared with the controls,the glucose metabolism of bilateral frontal cortices ( including the rectal gyrus,orbital gyrus and cingulate gyrus),left thalamus,right temporal lobe and bilateral cerebellum in refractory OCD patients increased significantly ( Zmax =3.45 - 5.80,all P ＜ 0.001 ).Bilateral motor cortices and bilateral parietal lobes (BA7),however,showed decreased glucose metabolism (Zmax =3.44 - 4.46,all P ＜0.001 ).Y-BOCS score was positively correlated with the glucose metabolism of the bilateral anterior cingulate cortex (Zmax =3.77,3.48 and 2.97,all P ＜ 0.01 ).Conclusions There is a characteristic metabolic pattern of increased glucose utilization in the fronto-striato-thalamic loop and decreased glucose utilization in bilateral motor cortices and parietal lobes in patients with OCD.The glucose metabolism in the anterior cingulate cortex might serve as a quantitative parameter for the assessment of the severity of OCD.Key words: Obsessive-oompulsive disorder; Brain; Tomography, emission-computed; Deoxyglucose" @default.
- W2590988692 created "2017-03-03" @default.
- W2590988692 creator A5031060869 @default.
- W2590988692 creator A5034821104 @default.
- W2590988692 creator A5036013509 @default.
- W2590988692 creator A5040589320 @default.
- W2590988692 creator A5067672283 @default.
- W2590988692 creator A5069296565 @default.
- W2590988692 creator A5085333943 @default.
- W2590988692 creator A5088740710 @default.
- W2590988692 date "2011-10-25" @default.
- W2590988692 modified "2023-09-28" @default.
- W2590988692 title "18F-FDG uptake changes in the brain functional loop in patients with refractory obsessive compulsive disorder" @default.
- W2590988692 hasPublicationYear "2011" @default.
- W2590988692 type Work @default.
- W2590988692 sameAs 2590988692 @default.
- W2590988692 citedByCount "0" @default.
- W2590988692 crossrefType "journal-article" @default.
- W2590988692 hasAuthorship W2590988692A5031060869 @default.
- W2590988692 hasAuthorship W2590988692A5034821104 @default.
- W2590988692 hasAuthorship W2590988692A5036013509 @default.
- W2590988692 hasAuthorship W2590988692A5040589320 @default.
- W2590988692 hasAuthorship W2590988692A5067672283 @default.
- W2590988692 hasAuthorship W2590988692A5069296565 @default.
- W2590988692 hasAuthorship W2590988692A5085333943 @default.
- W2590988692 hasAuthorship W2590988692A5088740710 @default.
- W2590988692 hasConcept C122129578 @default.
- W2590988692 hasConcept C126322002 @default.
- W2590988692 hasConcept C134018914 @default.
- W2590988692 hasConcept C15744967 @default.
- W2590988692 hasConcept C169760540 @default.
- W2590988692 hasConcept C169900460 @default.
- W2590988692 hasConcept C17093226 @default.
- W2590988692 hasConcept C2777127467 @default.
- W2590988692 hasConcept C2777348757 @default.
- W2590988692 hasConcept C2778180168 @default.
- W2590988692 hasConcept C2778402161 @default.
- W2590988692 hasConcept C2779246727 @default.
- W2590988692 hasConcept C2779369059 @default.
- W2590988692 hasConcept C2779652256 @default.
- W2590988692 hasConcept C71924100 @default.
- W2590988692 hasConceptScore W2590988692C122129578 @default.
- W2590988692 hasConceptScore W2590988692C126322002 @default.
- W2590988692 hasConceptScore W2590988692C134018914 @default.
- W2590988692 hasConceptScore W2590988692C15744967 @default.
- W2590988692 hasConceptScore W2590988692C169760540 @default.
- W2590988692 hasConceptScore W2590988692C169900460 @default.
- W2590988692 hasConceptScore W2590988692C17093226 @default.
- W2590988692 hasConceptScore W2590988692C2777127467 @default.
- W2590988692 hasConceptScore W2590988692C2777348757 @default.
- W2590988692 hasConceptScore W2590988692C2778180168 @default.
- W2590988692 hasConceptScore W2590988692C2778402161 @default.
- W2590988692 hasConceptScore W2590988692C2779246727 @default.
- W2590988692 hasConceptScore W2590988692C2779369059 @default.
- W2590988692 hasConceptScore W2590988692C2779652256 @default.
- W2590988692 hasConceptScore W2590988692C71924100 @default.
- W2590988692 hasIssue "05" @default.
- W2590988692 hasLocation W25909886921 @default.
- W2590988692 hasOpenAccess W2590988692 @default.
- W2590988692 hasPrimaryLocation W25909886921 @default.
- W2590988692 hasRelatedWork W1001505398 @default.
- W2590988692 hasRelatedWork W2021419670 @default.
- W2590988692 hasRelatedWork W2047183479 @default.
- W2590988692 hasRelatedWork W2065494735 @default.
- W2590988692 hasRelatedWork W2078129701 @default.
- W2590988692 hasRelatedWork W2121035887 @default.
- W2590988692 hasRelatedWork W2125285320 @default.
- W2590988692 hasRelatedWork W2139138258 @default.
- W2590988692 hasRelatedWork W2159852147 @default.
- W2590988692 hasRelatedWork W2279812309 @default.
- W2590988692 hasRelatedWork W2333887979 @default.
- W2590988692 hasRelatedWork W2356352710 @default.
- W2590988692 hasRelatedWork W2367866158 @default.
- W2590988692 hasRelatedWork W2386790684 @default.
- W2590988692 hasRelatedWork W2469188457 @default.
- W2590988692 hasRelatedWork W2768417013 @default.
- W2590988692 hasRelatedWork W2872592464 @default.
- W2590988692 hasRelatedWork W2946431406 @default.
- W2590988692 hasRelatedWork W3032464183 @default.
- W2590988692 hasRelatedWork W3048397761 @default.
- W2590988692 hasVolume "31" @default.
- W2590988692 isParatext "false" @default.
- W2590988692 isRetracted "false" @default.
- W2590988692 magId "2590988692" @default.
- W2590988692 workType "article" @default.