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- W2591172011 abstract "The first synthesis of substituted fluorenones directly from benzaldehydes and aryl iodides via a Pd(II)-catalyzed C(sp2)–H functionalization cascade is reported. Featuring anthranilic acid as an inexpensive transient directing group, the process is compatible with a variety of benzaldehydes and aryl iodides. A three-step synthesis of the antiviral drug Tilorone was completed in an excellent overall yield (40%), demonstrating the utility of this method." @default.
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- W2591172011 date "2017-02-22" @default.
- W2591172011 modified "2023-10-10" @default.
- W2591172011 title "Synthesis of Fluorenones from Benzaldehydes and Aryl Iodides: Dual C–H Functionalizations Using a Transient Directing Group" @default.
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- W2591172011 doi "https://doi.org/10.1021/acs.orglett.7b00161" @default.
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