Matches in SemOpenAlex for { <https://semopenalex.org/work/W259131489> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W259131489 endingPage "280" @default.
- W259131489 startingPage "254" @default.
- W259131489 abstract "The serum of fasting human subjects contains about ten times more insulin-like activity as measured on adipose tissue than immunoreactive insulin. The effect of the immunoreactive insulin in the serum on adipose tissue is completely neutralized by insulin antibodies and it has been designated as suppressible ILA (insulin-like activity). The insulin-like activity remaining in the serum after addition of insulin antibodies was called nonsuppressible ILA. Nonsuppressible ILA in the serum can be assigned to a large protein molecule (Mol. wt. between 70 and 150′000), the physiological role of which is unknown. No substantial variations of the level of nonsuppressible ILA in the serum were found in conditions accompanied by changes in carbohydrate and lipid metabolism. The molecule containing nonsuppressible ILA cannot be converted to insulin, and there are no good indications that the two substances are chemically related In recent years we have extracted a small molecule containing nonsuppressible ILA from a serum fraction. This molecule was partially purified to an activity of 20 mU/mg protein and it was found to have a molecular weight of approximately 6–8′000. This substance affects the metabolism of adipose tissue and muscle in vitro and in vivo in the same way as crystalline insulin; yet it is not suppressed under any circumstances by insulin antibodies and is chemically different from insulin. Our investigations on non suppressible ILA are discussed in view of the somewhat contradictory findings on other forms of ILA." @default.
- W259131489 created "2016-06-24" @default.
- W259131489 creator A5006604802 @default.
- W259131489 creator A5044394768 @default.
- W259131489 creator A5049479795 @default.
- W259131489 creator A5051147870 @default.
- W259131489 creator A5079081614 @default.
- W259131489 creator A5088576664 @default.
- W259131489 date "1969-01-01" @default.
- W259131489 modified "2023-10-14" @default.
- W259131489 title "Nicht hemmbare Insulinaktivität im menschlichen Serum: Physicochemische und biologische Eigenschaften nach partieller Reinigung" @default.
- W259131489 cites W1752411179 @default.
- W259131489 cites W1818968066 @default.
- W259131489 cites W1864285958 @default.
- W259131489 cites W1970164329 @default.
- W259131489 cites W1987145264 @default.
- W259131489 cites W1998516720 @default.
- W259131489 cites W2004554331 @default.
- W259131489 cites W2017593421 @default.
- W259131489 cites W2021199367 @default.
- W259131489 cites W2065802066 @default.
- W259131489 cites W2091326246 @default.
- W259131489 cites W2096356357 @default.
- W259131489 cites W2101387721 @default.
- W259131489 cites W2115250484 @default.
- W259131489 cites W2170500562 @default.
- W259131489 cites W2315352712 @default.
- W259131489 cites W2326737192 @default.
- W259131489 cites W2331794790 @default.
- W259131489 cites W2410368012 @default.
- W259131489 cites W2420226491 @default.
- W259131489 cites W242695552 @default.
- W259131489 cites W2462146819 @default.
- W259131489 cites W41328146 @default.
- W259131489 doi "https://doi.org/10.1016/b978-0-08-013395-9.50023-x" @default.
- W259131489 hasPublicationYear "1969" @default.
- W259131489 type Work @default.
- W259131489 sameAs 259131489 @default.
- W259131489 citedByCount "0" @default.
- W259131489 crossrefType "book-chapter" @default.
- W259131489 hasAuthorship W259131489A5006604802 @default.
- W259131489 hasAuthorship W259131489A5044394768 @default.
- W259131489 hasAuthorship W259131489A5049479795 @default.
- W259131489 hasAuthorship W259131489A5051147870 @default.
- W259131489 hasAuthorship W259131489A5079081614 @default.
- W259131489 hasAuthorship W259131489A5088576664 @default.
- W259131489 hasConcept C126322002 @default.
- W259131489 hasConcept C134018914 @default.
- W259131489 hasConcept C150903083 @default.
- W259131489 hasConcept C159654299 @default.
- W259131489 hasConcept C17093226 @default.
- W259131489 hasConcept C171089720 @default.
- W259131489 hasConcept C185592680 @default.
- W259131489 hasConcept C202751555 @default.
- W259131489 hasConcept C203014093 @default.
- W259131489 hasConcept C207001950 @default.
- W259131489 hasConcept C2779306644 @default.
- W259131489 hasConcept C55493867 @default.
- W259131489 hasConcept C62231903 @default.
- W259131489 hasConcept C71924100 @default.
- W259131489 hasConcept C86803240 @default.
- W259131489 hasConceptScore W259131489C126322002 @default.
- W259131489 hasConceptScore W259131489C134018914 @default.
- W259131489 hasConceptScore W259131489C150903083 @default.
- W259131489 hasConceptScore W259131489C159654299 @default.
- W259131489 hasConceptScore W259131489C17093226 @default.
- W259131489 hasConceptScore W259131489C171089720 @default.
- W259131489 hasConceptScore W259131489C185592680 @default.
- W259131489 hasConceptScore W259131489C202751555 @default.
- W259131489 hasConceptScore W259131489C203014093 @default.
- W259131489 hasConceptScore W259131489C207001950 @default.
- W259131489 hasConceptScore W259131489C2779306644 @default.
- W259131489 hasConceptScore W259131489C55493867 @default.
- W259131489 hasConceptScore W259131489C62231903 @default.
- W259131489 hasConceptScore W259131489C71924100 @default.
- W259131489 hasConceptScore W259131489C86803240 @default.
- W259131489 hasLocation W2591314891 @default.
- W259131489 hasOpenAccess W259131489 @default.
- W259131489 hasPrimaryLocation W2591314891 @default.
- W259131489 hasRelatedWork W1957106181 @default.
- W259131489 hasRelatedWork W2044897248 @default.
- W259131489 hasRelatedWork W2056633665 @default.
- W259131489 hasRelatedWork W2078141101 @default.
- W259131489 hasRelatedWork W2081564223 @default.
- W259131489 hasRelatedWork W2081817671 @default.
- W259131489 hasRelatedWork W2096423991 @default.
- W259131489 hasRelatedWork W2158888587 @default.
- W259131489 hasRelatedWork W2159949415 @default.
- W259131489 hasRelatedWork W2326715435 @default.
- W259131489 isParatext "false" @default.
- W259131489 isRetracted "false" @default.
- W259131489 magId "259131489" @default.
- W259131489 workType "book-chapter" @default.