Matches in SemOpenAlex for { <https://semopenalex.org/work/W2591448980> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2591448980 endingPage "258" @default.
- W2591448980 startingPage "258" @default.
- W2591448980 abstract "258 Background: Endoscopic ultrasound-directed fine needle aspiration (EUS-FNA) in combination with imaging is currently the standard preoperative diagnostic method for pancreatic ductal adenocarcinoma (PDA). Previous studies have reported sensitivities and specificities ranging from 80%-90% and accuracies of approximately 85%. Our goal was to determine the accuracy of EUS-FNA for detecting PDA in individual patients at our institution. Methods: We conducted a retrospective chart review using the Clinical Cancer Research Database at Huntsman Cancer Institute (HCI). We included all cases in which pancreatic lesions were evaluated by EUS-FNA and a subsequent surgical resection was performed. All patients that met these criteria at HCI between March 1999 and April 2014 were included. Descriptive variables were calculated by comparing EUS-FNA results to final surgical diagnoses. The variables used to determine these values were; false positive = PDA by EUS-FNA and negative at resection, true positive = PDA for both, false negative = negative for PDA at EUS-FNA and positive at resection, true negative = negative for both. We considered atypical cells positive for PDA since their presence mandates aggressive intervention by the treating clinician. Results: Of the 242 patients that met the inclusion criterion, 139 were female with an average age of 58 +/- 15 (mean +/- standard deviation) and 103 were male with an average age of 62 +/- 13. In terms of diagnosing PDA by EUS-FNA we determined the sensitivity 89% (81%-94%; 95% confidence interval), specificity 76% (68%-83%), positive predictive value of 74% (66%-82%), and negative predictive value 89% (82%-94%). Conclusions: Although our findings are relatively consistent with the current literature, there is discernible potential for inappropriate treatment of patients based purely on EUS-FNA evaluation. Limitations of this study are the appraisal at a single institution and the necessity to evaluate only cases that ultimately had surgical resection of the pancreatic lesion." @default.
- W2591448980 created "2017-03-03" @default.
- W2591448980 creator A5003013528 @default.
- W2591448980 creator A5004823813 @default.
- W2591448980 creator A5021880991 @default.
- W2591448980 creator A5026682286 @default.
- W2591448980 creator A5044574148 @default.
- W2591448980 creator A5046378649 @default.
- W2591448980 creator A5049173996 @default.
- W2591448980 creator A5053671455 @default.
- W2591448980 date "2015-01-20" @default.
- W2591448980 modified "2023-09-27" @default.
- W2591448980 title "Accuracy of diagnosing pancreatic ductal adenocarcinoma by EUS-FNA at a single institution." @default.
- W2591448980 doi "https://doi.org/10.1200/jco.2015.33.3_suppl.258" @default.
- W2591448980 hasPublicationYear "2015" @default.
- W2591448980 type Work @default.
- W2591448980 sameAs 2591448980 @default.
- W2591448980 citedByCount "1" @default.
- W2591448980 countsByYear W25914489802017 @default.
- W2591448980 crossrefType "journal-article" @default.
- W2591448980 hasAuthorship W2591448980A5003013528 @default.
- W2591448980 hasAuthorship W2591448980A5004823813 @default.
- W2591448980 hasAuthorship W2591448980A5021880991 @default.
- W2591448980 hasAuthorship W2591448980A5026682286 @default.
- W2591448980 hasAuthorship W2591448980A5044574148 @default.
- W2591448980 hasAuthorship W2591448980A5046378649 @default.
- W2591448980 hasAuthorship W2591448980A5049173996 @default.
- W2591448980 hasAuthorship W2591448980A5053671455 @default.
- W2591448980 hasConcept C121608353 @default.
- W2591448980 hasConcept C126322002 @default.
- W2591448980 hasConcept C126838900 @default.
- W2591448980 hasConcept C2775934546 @default.
- W2591448980 hasConcept C2776170712 @default.
- W2591448980 hasConcept C2780210213 @default.
- W2591448980 hasConcept C2780390042 @default.
- W2591448980 hasConcept C2781182431 @default.
- W2591448980 hasConcept C3019719930 @default.
- W2591448980 hasConcept C40993552 @default.
- W2591448980 hasConcept C44249647 @default.
- W2591448980 hasConcept C534262118 @default.
- W2591448980 hasConcept C53789813 @default.
- W2591448980 hasConcept C71924100 @default.
- W2591448980 hasConceptScore W2591448980C121608353 @default.
- W2591448980 hasConceptScore W2591448980C126322002 @default.
- W2591448980 hasConceptScore W2591448980C126838900 @default.
- W2591448980 hasConceptScore W2591448980C2775934546 @default.
- W2591448980 hasConceptScore W2591448980C2776170712 @default.
- W2591448980 hasConceptScore W2591448980C2780210213 @default.
- W2591448980 hasConceptScore W2591448980C2780390042 @default.
- W2591448980 hasConceptScore W2591448980C2781182431 @default.
- W2591448980 hasConceptScore W2591448980C3019719930 @default.
- W2591448980 hasConceptScore W2591448980C40993552 @default.
- W2591448980 hasConceptScore W2591448980C44249647 @default.
- W2591448980 hasConceptScore W2591448980C534262118 @default.
- W2591448980 hasConceptScore W2591448980C53789813 @default.
- W2591448980 hasConceptScore W2591448980C71924100 @default.
- W2591448980 hasIssue "3_suppl" @default.
- W2591448980 hasLocation W25914489801 @default.
- W2591448980 hasOpenAccess W2591448980 @default.
- W2591448980 hasPrimaryLocation W25914489801 @default.
- W2591448980 hasRelatedWork W1557667055 @default.
- W2591448980 hasRelatedWork W1606146065 @default.
- W2591448980 hasRelatedWork W2057092851 @default.
- W2591448980 hasRelatedWork W2091432527 @default.
- W2591448980 hasRelatedWork W2108137221 @default.
- W2591448980 hasRelatedWork W2316334368 @default.
- W2591448980 hasRelatedWork W2321741795 @default.
- W2591448980 hasRelatedWork W2536699695 @default.
- W2591448980 hasRelatedWork W2965490941 @default.
- W2591448980 hasRelatedWork W3159776338 @default.
- W2591448980 hasVolume "33" @default.
- W2591448980 isParatext "false" @default.
- W2591448980 isRetracted "false" @default.
- W2591448980 magId "2591448980" @default.
- W2591448980 workType "article" @default.