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- W2591492021 abstract "Purpose . To evaluate primary trabeculectomy with adjunctive mitomycin-C (MMC) in diabetic patients without retinopathy with primary angle-closure glaucoma (PACG). Design . This is a retrospective case series comparison. Participants . This retrospective trial compared outcomes of 88 eyes that underwent trabeculectomy in patients with diabetes mellitus (DM) without retinopathy and in 97 patients without DM. Methods . In this study, the intraocular pressure (IOP), visual acuity, visual field, and postoperative complications were compared between the two groups. Qualified surgical success is defined as an IOP between 6 and 18 mmHg with or without topical antiglaucoma medication. Results . After a follow-up of 5 years, the IOP decreased from a mean basal IOP of <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mn>27.8</mml:mn><mml:mo>±</mml:mo><mml:mn>7.3</mml:mn></mml:math> mmHg to <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mn>15.0</mml:mn><mml:mo>±</mml:mo><mml:mn>5.6</mml:mn></mml:math> mmHg in the DM group and from <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mn>27.3</mml:mn><mml:mo>±</mml:mo><mml:mn>6.0</mml:mn></mml:math> mmHg to <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mn>12.4</mml:mn><mml:mo>±</mml:mo><mml:mn>5.3</mml:mn></mml:math> mmHg in the control group. The mean number of antiglaucoma medications was <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M5><mml:mn>3.4</mml:mn><mml:mo>±</mml:mo><mml:mn>1.3</mml:mn></mml:math> and <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M6><mml:mn>3.3</mml:mn><mml:mo>±</mml:mo><mml:mn>1.2</mml:mn></mml:math> preoperatively (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M7><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.587</mml:mn></mml:math>) whereas it was <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M8><mml:mn>1.7</mml:mn><mml:mo>±</mml:mo><mml:mn>1.5</mml:mn></mml:math> and <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M9><mml:mn>1.1</mml:mn><mml:mo>±</mml:mo><mml:mn>1.4</mml:mn></mml:math> at the 5-year follow-up (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M10><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.049</mml:mn></mml:math>). The 5-year qualified surgical success rates were 42.9% and 65.4% for both groups (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M11><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.046</mml:mn></mml:math>; log-rank test). Encysted blebs were seen in 21 (23.9%) patients in the DM group and in 12 (12.4%) patients in the control group (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M12><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.041</mml:mn></mml:math>). Conclusion . PACG patients with DM without retinopathy undergoing primary trabeculectomy with MMC may have a lower long-term surgical survival rate compared with patients without DM." @default.
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- W2591492021 date "2017-01-01" @default.
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- W2591492021 title "Long-Term Outcomes of Primary Trabeculectomy in Diabetic Patients without Retinopathy with Primary Angle-Closure Glaucoma" @default.
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- W2591492021 doi "https://doi.org/10.1155/2017/7947854" @default.
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