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• W2591909105 endingPage "117906601769607" @default.
• W2591909105 startingPage "117906601769607" @default.
• W2591909105 abstract "Chorioamnionitis (CAM) is an important risk factor for the development of bronchopulmonary dysplasia (BPD) in preterm infants.To evaluate the effects of CAM on the development of BPD using interleukin 6 (IL-6), Krebs von den Lungen 6 (KL-6), and transforming growth factor β1 (TGF-β1) in the amniotic fluid as markers for inflammation, lung injury, and fibrosis/remodeling, respectively.Amniotic fluid concentrations of IL-6, KL-6, and TGF-β1 were measured with enzyme-linked immunosorbent assay or electro-chemiluminescence immunoassay.Of the 36 preterm infants, 18 were exposed to histologically confirmed CAM. Of these, 12 were later diagnosed as having BPD. The IL-6, KL-6, and TGF-β1 levels in the amniotic fluid significantly increased with increasing histologic severity of CAM. Moreover, these markers were higher in the BPD group with histologic CAM than those without.Our study suggests that CAM is likely to induce inflammatory, injury, and remodeling processes in the fetal lung." @default.
• W2591909105 created "2017-03-16" @default.
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• W2591909105 date "2017-01-01" @default.
• W2591909105 modified "2023-10-04" @default.
• W2591909105 title "Histologic Chorioamnionitis, Amniotic Fluid Interleukin 6, Krebs von den Lungen 6, and Transforming Growth Factor β₁for the Development of Neonatal Bronchopulmonary Dysplasia" @default.
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• W2591909105 doi "https://doi.org/10.1177/1179066017696076" @default.
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