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- W2592223981 endingPage "e0171859" @default.
- W2592223981 startingPage "e0171859" @default.
- W2592223981 abstract "Neocortical gamma activity is crucial for sensory perception and cognition. This study examines the value of using non-task stimulation-induced EEG oscillations to predict cognitive status in a birth cohort of healthy Danish males (Metropolit) with varying cognitive ability. In particular, we examine the steady-state VEP power response (SSVEP-PR) in the alpha (8Hz) and gamma (36Hz) bands in 54 males (avg. age: 62.0 years) and compare these with 10 young healthy participants (avg. age 27.6 years). Furthermore, we correlate the individual alpha-to-gamma difference in relative visual-area power (ΔRV) with cognitive scores for the older adults. We find that ΔRV decrease with age by just over one standard deviation when comparing young with old participants (p<0.01). Furthermore, intelligence is significantly negatively correlated with ΔRV in the older adult cohort, even when processing speed, global cognition, executive function, memory, and education (p<0.05). In our preferred specification, an increase in ΔRV of one standard deviation is associated with a reduction in intelligence of 48% of a standard deviation (p<0.01). Finally, we conclude that the difference in cerebral rhythmic activity between the alpha and gamma bands is associated with age and cognitive status, and that ΔRV therefore provide a non-subjective clinical tool with which to examine cognitive status in old age." @default.
- W2592223981 created "2017-03-16" @default.
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- W2592223981 date "2017-02-28" @default.
- W2592223981 modified "2023-10-14" @default.
- W2592223981 title "Visual steady state in relation to age and cognitive function" @default.
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- W2592223981 doi "https://doi.org/10.1371/journal.pone.0171859" @default.
- W2592223981 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5330460" @default.
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