FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2592295738> ?p ?o ?g. }

• W2592295738 endingPage "424" @default.
• W2592295738 startingPage "414" @default.
• W2592295738 abstract "ABSTRACT Atlantic cod are a commercially important species believed to be threatened by warming seas near their southern, equatorward upper thermal edge of distribution. Limitations to circulatory O2 transport, in particular cardiac output, and the geographic distribution of functionally different haemoglobin (Hb) genotypes have separately been suggested to play a role in setting thermal tolerance in this species. The present study assessed the thermal sensitivity of O2 binding in Atlantic cod red blood cells with different Hb genotypes near their upper thermal distribution limit and modelled its consequences for the arterio-venous O2 saturation difference, Sa–vO2, another major determinant of circulatory O2 supply rate. The results showed statistically indistinguishable red blood cell O2 binding between the three HbI genotypes in wild-caught Atlantic cod from the Irish Sea (53° N). Red blood cells had an unusually low O2 affinity, with reduced or even reversed thermal sensitivity between pH 7.4 and 7.9, and 5.0 and 20.0°C. This was paired with strongly pH-dependent affinity and cooperativity of red blood cell O2 binding (Bohr and Root effects). Modelling of Sa–vO2 at physiological pH, temperature and O2 partial pressures revealed a substantial capacity for increases in Sa–vO2 to meet rising tissue O2 demands at 5.0 and 12.5°C, but not at 20°C. Furthermore, there was no evidence for an increase of maximal Sa–vO2 with temperature. It is suggested that Atlantic cod at such high temperatures may solely depend on increases in cardiac output and blood O2 capacity, or thermal acclimatisation of metabolic rate, for matching circulatory O2 supply to tissue demand." @default.
• W2592295738 created "2017-03-16" @default.
• W2592295738 creator A5022340507 @default.
• W2592295738 creator A5027044006 @default.
• W2592295738 creator A5035950718 @default.
• W2592295738 creator A5070780221 @default.
• W2592295738 date "2017-02-01" @default.
• W2592295738 modified "2023-10-14" @default.
• W2592295738 title "Life on the edge: O2 binding in Atlantic cod red blood cells near their southern distribution limit is not sensitive to temperature or haemoglobin genotype" @default.
• W2592295738 cites W1193312474 @default.
• W2592295738 cites W1589774412 @default.
• W2592295738 cites W1592418946 @default.
• W2592295738 cites W160244221 @default.
• W2592295738 cites W1602853337 @default.
• W2592295738 cites W1685251144 @default.
• W2592295738 cites W179672401 @default.
• W2592295738 cites W1833458817 @default.
• W2592295738 cites W185717217 @default.
• W2592295738 cites W1881726039 @default.
• W2592295738 cites W1900879623 @default.
• W2592295738 cites W1963818329 @default.
• W2592295738 cites W1965253002 @default.
• W2592295738 cites W1971642120 @default.
• W2592295738 cites W1987554403 @default.
• W2592295738 cites W1991024712 @default.
• W2592295738 cites W2006991252 @default.
• W2592295738 cites W2007743446 @default.
• W2592295738 cites W2011842879 @default.
• W2592295738 cites W2017033659 @default.
• W2592295738 cites W2019497714 @default.
• W2592295738 cites W2021636695 @default.
• W2592295738 cites W2022461835 @default.
• W2592295738 cites W2028505482 @default.
• W2592295738 cites W2030129457 @default.
• W2592295738 cites W2032025721 @default.
• W2592295738 cites W2033524108 @default.
• W2592295738 cites W2035794017 @default.
• W2592295738 cites W2039821942 @default.
• W2592295738 cites W2041038986 @default.
• W2592295738 cites W2044063920 @default.
• W2592295738 cites W2050450384 @default.
• W2592295738 cites W2051285326 @default.
• W2592295738 cites W2053110663 @default.
• W2592295738 cites W2055063193 @default.
• W2592295738 cites W2064294458 @default.
• W2592295738 cites W2067674901 @default.
• W2592295738 cites W2073148293 @default.
• W2592295738 cites W2080061746 @default.
• W2592295738 cites W2080566394 @default.
• W2592295738 cites W2083323923 @default.
• W2592295738 cites W2084885321 @default.
• W2592295738 cites W2089166348 @default.
• W2592295738 cites W2091225698 @default.
• W2592295738 cites W2091892683 @default.
• W2592295738 cites W2105177238 @default.
• W2592295738 cites W2107976824 @default.
• W2592295738 cites W2113461506 @default.
• W2592295738 cites W2119727033 @default.
• W2592295738 cites W2125051521 @default.
• W2592295738 cites W2125171769 @default.
• W2592295738 cites W2126895474 @default.
• W2592295738 cites W2133259172 @default.
• W2592295738 cites W2134056986 @default.
• W2592295738 cites W2138221208 @default.
• W2592295738 cites W2141453190 @default.
• W2592295738 cites W2145360076 @default.
• W2592295738 cites W2148836432 @default.
• W2592295738 cites W2149814063 @default.
• W2592295738 cites W2150508075 @default.
• W2592295738 cites W2150869840 @default.
• W2592295738 cites W2152194437 @default.
• W2592295738 cites W2168909889 @default.
• W2592295738 cites W2182055620 @default.
• W2592295738 cites W2189272102 @default.
• W2592295738 cites W2201370601 @default.
• W2592295738 cites W2328626289 @default.
• W2592295738 cites W4301256303 @default.
• W2592295738 doi "https://doi.org/10.1242/jeb.141044" @default.
• W2592295738 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5312735" @default.
• W2592295738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28148818" @default.
• W2592295738 hasPublicationYear "2017" @default.
• W2592295738 type Work @default.
• W2592295738 sameAs 2592295738 @default.
• W2592295738 citedByCount "17" @default.
• W2592295738 countsByYear W25922957382017 @default.
• W2592295738 countsByYear W25922957382018 @default.
• W2592295738 countsByYear W25922957382019 @default.
• W2592295738 countsByYear W25922957382020 @default.
• W2592295738 countsByYear W25922957382022 @default.
• W2592295738 countsByYear W25922957382023 @default.
• W2592295738 crossrefType "journal-article" @default.
• W2592295738 hasAuthorship W2592295738A5022340507 @default.
• W2592295738 hasAuthorship W2592295738A5027044006 @default.
• W2592295738 hasAuthorship W2592295738A5035950718 @default.
• W2592295738 hasAuthorship W2592295738A5070780221 @default.
• W2592295738 hasBestOaLocation W25922957381 @default.
• W2592295738 hasConcept C107824862 @default.
• W2592295738 hasConcept C12554922 @default.

• next