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- W2592654520 abstract "This chapter focuses on recent efforts to incorporate the use of new clarification technologies during the production of antibodies. Precipitation/flocculation and depth filtration have been used traditionally as clarification methods, and knowledge of their capability in terms of impurity removal remains largely empirical. The chapter discusses the mechanism of action of various clarification technologies for simultaneous clarification and purification, as well as the technical issues and limitations affecting existing clarification technologies. Precipitation has long been used to purify proteins in the plasma protein industry and can play a significant role in the separation and enrichment of a target antibody. The purification of recombinant proteins carrying affinity fusion tags using affinity-based precipitation has been used successfully for many years. Flocculation can be used either to selectively flocculate target proteins or to flocculate impurities while leaving the target protein product in solution." @default.
- W2592654520 created "2017-03-16" @default.
- W2592654520 creator A5020861227 @default.
- W2592654520 creator A5083683996 @default.
- W2592654520 date "2017-03-03" @default.
- W2592654520 modified "2023-10-14" @default.
- W2592654520 title "NEXT‐GENERATION CLARIFICATION TECHNOLOGIES FOR THE DOWNSTREAM PROCESSING OF ANTIBODIES" @default.
- W2592654520 cites W1487060942 @default.
- W2592654520 cites W1504524108 @default.
- W2592654520 cites W1547937637 @default.
- W2592654520 cites W1585784812 @default.
- W2592654520 cites W1609743519 @default.
- W2592654520 cites W1918215484 @default.
- W2592654520 cites W1956733547 @default.
- W2592654520 cites W1976814131 @default.
- W2592654520 cites W1978274050 @default.
- W2592654520 cites W1980414015 @default.
- W2592654520 cites W1980712329 @default.
- W2592654520 cites W1982222591 @default.
- W2592654520 cites W1982941857 @default.
- W2592654520 cites W1985679694 @default.
- W2592654520 cites W1987328338 @default.
- W2592654520 cites W1989455652 @default.
- W2592654520 cites W1989801492 @default.
- W2592654520 cites W1991402143 @default.
- W2592654520 cites W1992816819 @default.
- W2592654520 cites W1993598516 @default.
- W2592654520 cites W1997014510 @default.
- W2592654520 cites W1999676021 @default.
- W2592654520 cites W2002005540 @default.
- W2592654520 cites W2004048780 @default.
- W2592654520 cites W2004492657 @default.
- W2592654520 cites W2005579644 @default.
- W2592654520 cites W2010341763 @default.
- W2592654520 cites W2011362270 @default.
- W2592654520 cites W2012374222 @default.
- W2592654520 cites W2017687723 @default.
- W2592654520 cites W2018569753 @default.
- W2592654520 cites W2020175184 @default.
- W2592654520 cites W2020950916 @default.
- W2592654520 cites W2021900417 @default.
- W2592654520 cites W2022018618 @default.
- W2592654520 cites W2022814920 @default.
- W2592654520 cites W2023805450 @default.
- W2592654520 cites W2023876635 @default.
- W2592654520 cites W2025013543 @default.
- W2592654520 cites W2025559460 @default.
- W2592654520 cites W2029878671 @default.
- W2592654520 cites W2030637083 @default.
- W2592654520 cites W2033924510 @default.
- W2592654520 cites W2034568372 @default.
- W2592654520 cites W2035354173 @default.
- W2592654520 cites W2036073897 @default.
- W2592654520 cites W2037551042 @default.
- W2592654520 cites W2037768416 @default.
- W2592654520 cites W2041066564 @default.
- W2592654520 cites W2042379506 @default.
- W2592654520 cites W2044199954 @default.
- W2592654520 cites W2046870528 @default.
- W2592654520 cites W2047736099 @default.
- W2592654520 cites W2048649292 @default.
- W2592654520 cites W2051430573 @default.
- W2592654520 cites W2053314207 @default.
- W2592654520 cites W2056206157 @default.
- W2592654520 cites W2056433388 @default.
- W2592654520 cites W2056621656 @default.
- W2592654520 cites W2056729915 @default.
- W2592654520 cites W2057684068 @default.
- W2592654520 cites W2058198081 @default.
- W2592654520 cites W2059489323 @default.
- W2592654520 cites W2060845774 @default.
- W2592654520 cites W2061639704 @default.
- W2592654520 cites W2061778374 @default.
- W2592654520 cites W2062475341 @default.
- W2592654520 cites W2063494157 @default.
- W2592654520 cites W2065983143 @default.
- W2592654520 cites W2066833805 @default.
- W2592654520 cites W2068635250 @default.
- W2592654520 cites W2073430339 @default.
- W2592654520 cites W2073813597 @default.
- W2592654520 cites W2076367767 @default.
- W2592654520 cites W2076971609 @default.
- W2592654520 cites W2077007857 @default.
- W2592654520 cites W2077217784 @default.
- W2592654520 cites W2077965850 @default.
- W2592654520 cites W2080654103 @default.
- W2592654520 cites W2083017360 @default.
- W2592654520 cites W2085123622 @default.
- W2592654520 cites W2094052190 @default.
- W2592654520 cites W2094286330 @default.
- W2592654520 cites W2095159742 @default.
- W2592654520 cites W2100416033 @default.
- W2592654520 cites W2101387721 @default.
- W2592654520 cites W2101545092 @default.
- W2592654520 cites W2102051899 @default.
- W2592654520 cites W2103147366 @default.
- W2592654520 cites W2104958969 @default.
- W2592654520 cites W2109360810 @default.