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- W2592658064 abstract "Sickle cell disease (SCD) is a hereditary red cell disorder with clinical manifestations secondary to sickling or crescent-shaped distortion of the red blood cells. Major clinical manifestations of SCD include haemolytic anaemia and vaso-occlusive phenomena resulting in ischaemic tissue injury and organ damage. Chronic sequelae of the anaemia and vaso-occlusive processes involving the musculoskeletal system include complications related to extramedullary haematopoiesis, osteonecrosis, myonecrosis and osteomyelitis. Sickle cell bone disease is one of the commonest clinical presentations. Awareness and knowledge of the imaging features related to these complications are essential for early diagnosis and prompt management. In this article, the pathophysiology and key imaging findings related to these complications are reviewed." @default.
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- W2592658064 date "2017-05-01" @default.
- W2592658064 modified "2023-09-24" @default.
- W2592658064 title "Imaging of musculoskeletal manifestations in sickle cell disease patients" @default.
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- W2592658064 doi "https://doi.org/10.1259/bjr.20160130" @default.
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