Matches in SemOpenAlex for { <https://semopenalex.org/work/W2592682214> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2592682214 endingPage "295" @default.
- W2592682214 startingPage "287" @default.
- W2592682214 abstract "KL-6 is a biomarker of the severity of pulmonary alveolar proteinosis (PAP). We noticed a significant difference in the mean serum KL-6 level between Japanese and Caucasian patients. To assess the clinical value of serum KL-6 in Chinese PAP patients, and to compare the differences in serum KL-6 levels in Chinese patients and patients of other ethnicities.From 2014-2016, we prospectively examined 37 Chinese Han patients with PAP, measured their serum KL-6 levels, evaluated the correlation between initial KL-6 levels and clinical variables, and compared our results with studies from Japan and Germany (similar methods were used). We searched dbSNP for the MUC1 568 (rs4072037) genotype or allele frequency distributions in China, Japan, and Germany.Initial serum KL-6 levels were significantly correlated with baseline PaO2, A-aDO2, DLCO, FVC, and LDH levels (all P<0.001). Compared with Chinese PAP patients, the mean serum KL-6 level was significantly lower in German PAP patients (P<0.001) but not in Japanese PAP patients (P>0.4). In the rs4072037 allele frequency distributions, the frequency of the A/A genotype was significantly higher while that of the G/G genotype was significantly lower in Chinese and Japanese cohorts than in Caucasian cohorts (both P<0.001).Serum KL-6 can be used as a biological indicator for disease monitoring in Chinese patients. The difference in serum KL-6 level among Chinese, German, and Japanese PAP patients may be associated with the distribution of the rs4072037 genotype." @default.
- W2592682214 created "2017-03-16" @default.
- W2592682214 creator A5004837173 @default.
- W2592682214 creator A5016866677 @default.
- W2592682214 creator A5035958047 @default.
- W2592682214 creator A5048339590 @default.
- W2592682214 creator A5052676364 @default.
- W2592682214 creator A5071074966 @default.
- W2592682214 creator A5090236648 @default.
- W2592682214 date "2017-02-01" @default.
- W2592682214 modified "2023-09-23" @default.
- W2592682214 title "Serum KL-6 in pulmonary alveolar proteinosis: China compared historically with Germany and Japan" @default.
- W2592682214 cites W1945770691 @default.
- W2592682214 cites W1975308804 @default.
- W2592682214 cites W2004223821 @default.
- W2592682214 cites W2031246383 @default.
- W2592682214 cites W2072689349 @default.
- W2592682214 cites W2094909945 @default.
- W2592682214 cites W2113740916 @default.
- W2592682214 cites W2136497489 @default.
- W2592682214 cites W2141506289 @default.
- W2592682214 cites W2156412424 @default.
- W2592682214 cites W2171709078 @default.
- W2592682214 cites W2431992038 @default.
- W2592682214 cites W2989337141 @default.
- W2592682214 doi "https://doi.org/10.21037/jtd.2017.02.14" @default.
- W2592682214 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5334078" @default.
- W2592682214 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28275476" @default.
- W2592682214 hasPublicationYear "2017" @default.
- W2592682214 type Work @default.
- W2592682214 sameAs 2592682214 @default.
- W2592682214 citedByCount "5" @default.
- W2592682214 countsByYear W25926822142019 @default.
- W2592682214 countsByYear W25926822142021 @default.
- W2592682214 countsByYear W25926822142022 @default.
- W2592682214 countsByYear W25926822142023 @default.
- W2592682214 crossrefType "journal-article" @default.
- W2592682214 hasAuthorship W2592682214A5004837173 @default.
- W2592682214 hasAuthorship W2592682214A5016866677 @default.
- W2592682214 hasAuthorship W2592682214A5035958047 @default.
- W2592682214 hasAuthorship W2592682214A5048339590 @default.
- W2592682214 hasAuthorship W2592682214A5052676364 @default.
- W2592682214 hasAuthorship W2592682214A5071074966 @default.
- W2592682214 hasAuthorship W2592682214A5090236648 @default.
- W2592682214 hasBestOaLocation W25926822142 @default.
- W2592682214 hasConcept C104317684 @default.
- W2592682214 hasConcept C126322002 @default.
- W2592682214 hasConcept C135763542 @default.
- W2592682214 hasConcept C16020263 @default.
- W2592682214 hasConcept C165637977 @default.
- W2592682214 hasConcept C185592680 @default.
- W2592682214 hasConcept C2777714996 @default.
- W2592682214 hasConcept C2778972612 @default.
- W2592682214 hasConcept C2781197716 @default.
- W2592682214 hasConcept C3018587741 @default.
- W2592682214 hasConcept C55493867 @default.
- W2592682214 hasConcept C71924100 @default.
- W2592682214 hasConcept C90924648 @default.
- W2592682214 hasConceptScore W2592682214C104317684 @default.
- W2592682214 hasConceptScore W2592682214C126322002 @default.
- W2592682214 hasConceptScore W2592682214C135763542 @default.
- W2592682214 hasConceptScore W2592682214C16020263 @default.
- W2592682214 hasConceptScore W2592682214C165637977 @default.
- W2592682214 hasConceptScore W2592682214C185592680 @default.
- W2592682214 hasConceptScore W2592682214C2777714996 @default.
- W2592682214 hasConceptScore W2592682214C2778972612 @default.
- W2592682214 hasConceptScore W2592682214C2781197716 @default.
- W2592682214 hasConceptScore W2592682214C3018587741 @default.
- W2592682214 hasConceptScore W2592682214C55493867 @default.
- W2592682214 hasConceptScore W2592682214C71924100 @default.
- W2592682214 hasConceptScore W2592682214C90924648 @default.
- W2592682214 hasIssue "2" @default.
- W2592682214 hasLocation W25926822141 @default.
- W2592682214 hasLocation W25926822142 @default.
- W2592682214 hasLocation W25926822143 @default.
- W2592682214 hasLocation W25926822144 @default.
- W2592682214 hasOpenAccess W2592682214 @default.
- W2592682214 hasPrimaryLocation W25926822141 @default.
- W2592682214 hasRelatedWork W1903843037 @default.
- W2592682214 hasRelatedWork W1985718437 @default.
- W2592682214 hasRelatedWork W2147285037 @default.
- W2592682214 hasRelatedWork W2149376641 @default.
- W2592682214 hasRelatedWork W2312886132 @default.
- W2592682214 hasRelatedWork W2557568362 @default.
- W2592682214 hasRelatedWork W2570651842 @default.
- W2592682214 hasRelatedWork W3044135017 @default.
- W2592682214 hasRelatedWork W3171885048 @default.
- W2592682214 hasRelatedWork W4235645481 @default.
- W2592682214 hasVolume "9" @default.
- W2592682214 isParatext "false" @default.
- W2592682214 isRetracted "false" @default.
- W2592682214 magId "2592682214" @default.
- W2592682214 workType "article" @default.