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- W2592830812 abstract "Paratuberculosis, also known as Johne's disease or JD, is a chronic contagiousinfection, caused by Mycobaterium avium paratuberculosis (MAP). This fatal diseaseis incurable and causes considerable economic losses to the industry. Each year, theU.S. dairy industry loses over 200 million dollars due to the infection. Using the cattlemovement data of six California dairy farms and Johne's disease transmission data, amathematical model was developed to determine control policies that can minimizethe likelihood of outbreaks and the incidence and prevalence of the infection in dairyfarms. In particular, we have implemented a hybrid modeling approach that combinesthe between-pen cattle movements with progression of the infection in each pen tostudy the effect of cattle movement patterns on the spread of disease. Using the basicreproduction number, the infection risk in cattle in each pen and the entire farm wascalculated. It is shown that the overall infection risk is substantially reduced whenthe average residence time and the population size in high risk pens are minimized.Using numerical simulations, spread of epidemic waves in dairy farms and impacts of control measures are numerically explored. It is shown that a single control measureis insufficient to prevent outbreaks. Whereas a combination of control measures suchas test and cull, and intensive pen cleaning may lead to a disease-free environment inthe dairy farms." @default.
- W2592830812 created "2017-03-16" @default.
- W2592830812 creator A5075508374 @default.
- W2592830812 date "2016-01-01" @default.
- W2592830812 modified "2023-09-23" @default.
- W2592830812 title "A Hybrid Modeling Approach to Assess the Efficacy of Control Measures on Paratuberculosis on U.S. Dairy Farms" @default.
- W2592830812 hasPublicationYear "2016" @default.
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