FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2592913906> ?p ?o ?g. }

• W2592913906 endingPage "340" @default.
• W2592913906 startingPage "331" @default.
• W2592913906 abstract "Ras-related protein 25 (Rab25) is a member of the Rab family, and it has been reported to play an important role in tumorigenesis. However, its direct involvement in human glioblastoma multiforme (GBM) is still unclear. The aim of the current study was to investigate the potential role of Rab25 in the growth, proliferation, invasion, and migration of human GBM. Our results showed that Rab25 expression was significantly higher in human GBM cell lines compared with a normal astrocyte cell line. In vitro functional studies revealed that knockdown of Rab25 reduced cell proliferation and inhibited invasion and migration of GBM cells. In vivo experiments showed that knockdown of Rab25 attenuated the tumor growth in nude mice. Finally, knockdown of Rab25 significantly inhibited the phosphorylation levels of PI3K and AKT in GBM cells. Taken together, these findings indicate that Rab25 may act as a tumor promoter in human GBM and that approaches to target Rab25 may provide a novel strategy to treat this disease." @default.
• W2592913906 created "2017-03-16" @default.
• W2592913906 creator A5009598772 @default.
• W2592913906 creator A5061543595 @default.
• W2592913906 creator A5063582009 @default.
• W2592913906 creator A5065785367 @default.
• W2592913906 creator A5066543200 @default.
• W2592913906 creator A5080793559 @default.
• W2592913906 creator A5081372402 @default.
• W2592913906 date "2017-03-13" @default.
• W2592913906 modified "2023-10-17" @default.
• W2592913906 title "Knockdown of Ras-Related Protein 25 (Rab25) Inhibits the In Vitro Cytotoxicity and In Vivo Antitumor Activity of Human Glioblastoma Multiforme Cells" @default.
• W2592913906 cites W1489286522 @default.
• W2592913906 cites W1508367694 @default.
• W2592913906 cites W1516244929 @default.
• W2592913906 cites W1593585240 @default.
• W2592913906 cites W1854354632 @default.
• W2592913906 cites W1967396842 @default.
• W2592913906 cites W1980695842 @default.
• W2592913906 cites W1992273782 @default.
• W2592913906 cites W1994668150 @default.
• W2592913906 cites W2001499831 @default.
• W2592913906 cites W2011939769 @default.
• W2592913906 cites W2022387762 @default.
• W2592913906 cites W2026260372 @default.
• W2592913906 cites W2033390879 @default.
• W2592913906 cites W2041134111 @default.
• W2592913906 cites W2052309340 @default.
• W2592913906 cites W2078636414 @default.
• W2592913906 cites W2107711629 @default.
• W2592913906 cites W2112559300 @default.
• W2592913906 cites W2112564899 @default.
• W2592913906 cites W2112751496 @default.
• W2592913906 cites W2130355910 @default.
• W2592913906 cites W2158681922 @default.
• W2592913906 cites W2171945016 @default.
• W2592913906 doi "https://doi.org/10.3727/096504016x14736286083065" @default.
• W2592913906 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7841148" @default.
• W2592913906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28281975" @default.
• W2592913906 hasPublicationYear "2017" @default.
• W2592913906 type Work @default.
• W2592913906 sameAs 2592913906 @default.
• W2592913906 citedByCount "11" @default.
• W2592913906 countsByYear W25929139062017 @default.
• W2592913906 countsByYear W25929139062018 @default.
• W2592913906 countsByYear W25929139062019 @default.
• W2592913906 countsByYear W25929139062021 @default.
• W2592913906 countsByYear W25929139062022 @default.
• W2592913906 countsByYear W25929139062023 @default.
• W2592913906 crossrefType "journal-article" @default.
• W2592913906 hasAuthorship W2592913906A5009598772 @default.
• W2592913906 hasAuthorship W2592913906A5061543595 @default.
• W2592913906 hasAuthorship W2592913906A5063582009 @default.
• W2592913906 hasAuthorship W2592913906A5065785367 @default.
• W2592913906 hasAuthorship W2592913906A5066543200 @default.
• W2592913906 hasAuthorship W2592913906A5080793559 @default.
• W2592913906 hasAuthorship W2592913906A5081372402 @default.
• W2592913906 hasBestOaLocation W25929139062 @default.
• W2592913906 hasConcept C121608353 @default.
• W2592913906 hasConcept C150903083 @default.
• W2592913906 hasConcept C173396325 @default.
• W2592913906 hasConcept C185592680 @default.
• W2592913906 hasConcept C202751555 @default.
• W2592913906 hasConcept C207001950 @default.
• W2592913906 hasConcept C502942594 @default.
• W2592913906 hasConcept C54355233 @default.
• W2592913906 hasConcept C55493867 @default.
• W2592913906 hasConcept C555283112 @default.
• W2592913906 hasConcept C62112901 @default.
• W2592913906 hasConcept C62478195 @default.
• W2592913906 hasConcept C75217442 @default.
• W2592913906 hasConcept C81885089 @default.
• W2592913906 hasConcept C86554907 @default.
• W2592913906 hasConcept C86803240 @default.
• W2592913906 hasConcept C95444343 @default.
• W2592913906 hasConceptScore W2592913906C121608353 @default.
• W2592913906 hasConceptScore W2592913906C150903083 @default.
• W2592913906 hasConceptScore W2592913906C173396325 @default.
• W2592913906 hasConceptScore W2592913906C185592680 @default.
• W2592913906 hasConceptScore W2592913906C202751555 @default.
• W2592913906 hasConceptScore W2592913906C207001950 @default.
• W2592913906 hasConceptScore W2592913906C502942594 @default.
• W2592913906 hasConceptScore W2592913906C54355233 @default.
• W2592913906 hasConceptScore W2592913906C55493867 @default.
• W2592913906 hasConceptScore W2592913906C555283112 @default.
• W2592913906 hasConceptScore W2592913906C62112901 @default.
• W2592913906 hasConceptScore W2592913906C62478195 @default.
• W2592913906 hasConceptScore W2592913906C75217442 @default.
• W2592913906 hasConceptScore W2592913906C81885089 @default.
• W2592913906 hasConceptScore W2592913906C86554907 @default.
• W2592913906 hasConceptScore W2592913906C86803240 @default.
• W2592913906 hasConceptScore W2592913906C95444343 @default.
• W2592913906 hasIssue "3" @default.
• W2592913906 hasLocation W25929139061 @default.
• W2592913906 hasLocation W25929139062 @default.
• W2592913906 hasOpenAccess W2592913906 @default.
• W2592913906 hasPrimaryLocation W25929139061 @default.
• W2592913906 hasRelatedWork W1557020267 @default.

• next