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- W2593022018 abstract "A 3,7-diazabicyclo[3.3.1]nonane linking to two melamines is a unique transmembrane H+/Cl− carrier. In the solid state, the V-shaped compound forms a HCl-bound zig-zag network through cooperative protonation and hydrogen bond interactions. In the lipid membrane, the receptor forms a dimeric self-assembly involving multiple H+ and Cl− leading to the efficient transport of the acid. The pH-dependent Cl− efflux observed for the compound was rationalized based on a gradual protonation model that confers an active transmembrane carrier at physiological pH." @default.
- W2593022018 created "2017-03-16" @default.
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- W2593022018 date "2017-03-09" @default.
- W2593022018 modified "2023-09-26" @default.
- W2593022018 title "A Dimeric Bis(melamine)-Substituted Bispidine for Efficient Transmembrane H<sup>+</sup>/Cl<sup>−</sup>Cotransport" @default.
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- W2593022018 doi "https://doi.org/10.1002/anie.201700803" @default.
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