FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2593176507> ?p ?o ?g. }

• W2593176507 endingPage "1950" @default.
• W2593176507 startingPage "1939" @default.
• W2593176507 abstract "Model-based economic evaluation was performed to assess the cost-effectiveness of zoledronic acid. Although zoledronic acid was dominated by alendronate, the incremental quality-adjusted life year (QALY) was quite small in extent. Considering the advantage of once-yearly injection of zoledronic acid in persistence, zoledronic acid might be a cost-effective treatment option compared to once-weekly oral alendronate.The purpose of this study was to estimate the cost-effectiveness of once-yearly injection of zoledronic acid for the treatment of osteoporosis in Japan.A patient-level state-transition model was developed to predict the outcome of patients with osteoporosis who have experienced a previous vertebral fracture. The efficacy of zoledronic acid was derived from a published network meta-analysis. Lifetime cost and QALYs were estimated for patients who had received zoledronic acid, alendronate, or basic treatment alone. The incremental cost-effectiveness ratio (ICER) of zoledronic acid was estimated.For patients 70 years of age, zoledronic acid was dominated by alendronate with incremental QALY of -0.004 to -0.000 and incremental cost of 430 USD to 493 USD. Deterministic sensitivity analysis indicated that the relative risk of hip fracture and drug cost strongly affected the cost-effectiveness of zoledronic acid compared to alendronate. Scenario analysis considering treatment persistence showed that the ICER of zoledronic acid compared to alendronate was estimated to be 47,435 USD, 27,018 USD, and 10,749 USD per QALY gained for patients with a T-score of -2.0, -2.5, or -3.0, respectively.Although zoledronic acid is dominated by alendronate, the incremental QALY is quite small in extent. Considering the advantage of annual zoledronic acid treatment in compliance and persistence, zoledronic acid may be a cost-effective treatment option compared to alendronate." @default.
• W2593176507 created "2017-03-16" @default.
• W2593176507 creator A5025363249 @default.
• W2593176507 creator A5037094831 @default.
• W2593176507 creator A5078379776 @default.
• W2593176507 date "2017-03-06" @default.
• W2593176507 modified "2023-09-26" @default.
• W2593176507 title "Cost-effectiveness analysis of once-yearly injection of zoledronic acid for the treatment of osteoporosis in Japan" @default.
• W2593176507 cites W1486043180 @default.
• W2593176507 cites W183496749 @default.
• W2593176507 cites W1993035292 @default.
• W2593176507 cites W2001110947 @default.
• W2593176507 cites W2007495763 @default.
• W2593176507 cites W2014026657 @default.
• W2593176507 cites W2019022588 @default.
• W2593176507 cites W2027446722 @default.
• W2593176507 cites W2036125852 @default.
• W2593176507 cites W2050587934 @default.
• W2593176507 cites W2057197703 @default.
• W2593176507 cites W2058987411 @default.
• W2593176507 cites W2066375830 @default.
• W2593176507 cites W2072809955 @default.
• W2593176507 cites W2073113169 @default.
• W2593176507 cites W2074677838 @default.
• W2593176507 cites W2077494568 @default.
• W2593176507 cites W2080442644 @default.
• W2593176507 cites W2096967244 @default.
• W2593176507 cites W2101285723 @default.
• W2593176507 cites W2103599857 @default.
• W2593176507 cites W2113686143 @default.
• W2593176507 cites W2134522439 @default.
• W2593176507 cites W2135860949 @default.
• W2593176507 cites W2143254851 @default.
• W2593176507 cites W2150727876 @default.
• W2593176507 cites W2150785441 @default.
• W2593176507 cites W2158331079 @default.
• W2593176507 cites W2161837912 @default.
• W2593176507 cites W2181882121 @default.
• W2593176507 cites W2228651061 @default.
• W2593176507 cites W2316951001 @default.
• W2593176507 cites W2412041195 @default.
• W2593176507 cites W2416426245 @default.
• W2593176507 cites W2421956978 @default.
• W2593176507 doi "https://doi.org/10.1007/s00198-017-3973-8" @default.
• W2593176507 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6828016" @default.
• W2593176507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28324132" @default.
• W2593176507 hasPublicationYear "2017" @default.
• W2593176507 type Work @default.
• W2593176507 sameAs 2593176507 @default.
• W2593176507 citedByCount "13" @default.
• W2593176507 countsByYear W25931765072018 @default.
• W2593176507 countsByYear W25931765072019 @default.
• W2593176507 countsByYear W25931765072020 @default.
• W2593176507 countsByYear W25931765072021 @default.
• W2593176507 countsByYear W25931765072022 @default.
• W2593176507 crossrefType "journal-article" @default.
• W2593176507 hasAuthorship W2593176507A5025363249 @default.
• W2593176507 hasAuthorship W2593176507A5037094831 @default.
• W2593176507 hasAuthorship W2593176507A5078379776 @default.
• W2593176507 hasBestOaLocation W25931765071 @default.
• W2593176507 hasConcept C126322002 @default.
• W2593176507 hasConcept C2776326535 @default.
• W2593176507 hasConcept C2776541429 @default.
• W2593176507 hasConcept C71924100 @default.
• W2593176507 hasConceptScore W2593176507C126322002 @default.
• W2593176507 hasConceptScore W2593176507C2776326535 @default.
• W2593176507 hasConceptScore W2593176507C2776541429 @default.
• W2593176507 hasConceptScore W2593176507C71924100 @default.
• W2593176507 hasFunder F4320312288 @default.
• W2593176507 hasIssue "6" @default.
• W2593176507 hasLocation W25931765071 @default.
• W2593176507 hasLocation W25931765072 @default.
• W2593176507 hasLocation W25931765073 @default.
• W2593176507 hasLocation W25931765074 @default.
• W2593176507 hasOpenAccess W2593176507 @default.
• W2593176507 hasPrimaryLocation W25931765071 @default.
• W2593176507 hasRelatedWork W1998611688 @default.
• W2593176507 hasRelatedWork W2023234727 @default.
• W2593176507 hasRelatedWork W2066082630 @default.
• W2593176507 hasRelatedWork W2078392470 @default.
• W2593176507 hasRelatedWork W2101347557 @default.
• W2593176507 hasRelatedWork W2164050024 @default.
• W2593176507 hasRelatedWork W2390541474 @default.
• W2593176507 hasRelatedWork W2461888162 @default.
• W2593176507 hasRelatedWork W3035095394 @default.
• W2593176507 hasRelatedWork W4309691976 @default.
• W2593176507 hasVolume "28" @default.
• W2593176507 isParatext "false" @default.
• W2593176507 isRetracted "false" @default.
• W2593176507 magId "2593176507" @default.
• W2593176507 workType "article" @default.