Matches in SemOpenAlex for { <https://semopenalex.org/work/W2593272302> ?p ?o ?g. }
- W2593272302 endingPage "188" @default.
- W2593272302 startingPage "177" @default.
- W2593272302 abstract "Traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD) have previously been reported to be associated with increased risk of Alzheimer's disease (AD). We are using biomarkers to study Vietnam Veterans with/without mild cognitive impairment with a history of at least one TBI and/or ongoing PTSD to determine whether these contribute to the development of AD.Potential subjects identified by Veterans Administration records underwent an initial telephone screen. Consented subjects underwent clinical evaluation, lumbar puncture, structural MRI and amyloid PET scans.We observed worse cognitive functioning in PTSD and TBI + PTSD groups, worse global cognitive functioning in the PTSD group, lower superior parietal volume in the TBI + PTSD group, and lower amyloid positivity in the PTSD group, but not the TBI group compared to controls without TBI/PTSD. Medial temporal lobe atrophy was not increased in the PTSD and/or TBI groups.Preliminary results do not indicate that TBI or PTSD increase the risk for AD measured by amyloid PET. Additional recruitment, longitudinal follow-up, and tau PET scans will provide more information in the future." @default.
- W2593272302 created "2017-03-16" @default.
- W2593272302 creator A5005099850 @default.
- W2593272302 creator A5009052142 @default.
- W2593272302 creator A5016442996 @default.
- W2593272302 creator A5034225628 @default.
- W2593272302 creator A5036678938 @default.
- W2593272302 creator A5043086041 @default.
- W2593272302 creator A5045246745 @default.
- W2593272302 creator A5053096250 @default.
- W2593272302 creator A5053705093 @default.
- W2593272302 creator A5071825455 @default.
- W2593272302 creator A5079147812 @default.
- W2593272302 creator A5086120667 @default.
- W2593272302 creator A5090855876 @default.
- W2593272302 date "2017-03-12" @default.
- W2593272302 modified "2023-10-11" @default.
- W2593272302 title "Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer's disease in Vietnam Veterans using the Alzheimer's Disease Neuroimaging Initiative: Preliminary report" @default.
- W2593272302 cites W1271702090 @default.
- W2593272302 cites W1525288136 @default.
- W2593272302 cites W1701655062 @default.
- W2593272302 cites W170792860 @default.
- W2593272302 cites W1761166871 @default.
- W2593272302 cites W1797408175 @default.
- W2593272302 cites W1843733636 @default.
- W2593272302 cites W1887821162 @default.
- W2593272302 cites W1906409993 @default.
- W2593272302 cites W1919272385 @default.
- W2593272302 cites W1939082208 @default.
- W2593272302 cites W1968401437 @default.
- W2593272302 cites W1969969013 @default.
- W2593272302 cites W1970283678 @default.
- W2593272302 cites W1971896998 @default.
- W2593272302 cites W1972243699 @default.
- W2593272302 cites W1974452119 @default.
- W2593272302 cites W1975656204 @default.
- W2593272302 cites W1977917379 @default.
- W2593272302 cites W1982224220 @default.
- W2593272302 cites W1985918201 @default.
- W2593272302 cites W1986301740 @default.
- W2593272302 cites W1989282675 @default.
- W2593272302 cites W1991516886 @default.
- W2593272302 cites W1997405299 @default.
- W2593272302 cites W2001091274 @default.
- W2593272302 cites W2002123847 @default.
- W2593272302 cites W2004412496 @default.
- W2593272302 cites W2004651961 @default.
- W2593272302 cites W2007453010 @default.
- W2593272302 cites W2007898025 @default.
- W2593272302 cites W2010734852 @default.
- W2593272302 cites W2011811675 @default.
- W2593272302 cites W2013090392 @default.
- W2593272302 cites W2017471497 @default.
- W2593272302 cites W2023349410 @default.
- W2593272302 cites W2023605059 @default.
- W2593272302 cites W2023819682 @default.
- W2593272302 cites W2024382752 @default.
- W2593272302 cites W2025639109 @default.
- W2593272302 cites W2027500465 @default.
- W2593272302 cites W2032843602 @default.
- W2593272302 cites W2034225478 @default.
- W2593272302 cites W2035445406 @default.
- W2593272302 cites W204562422 @default.
- W2593272302 cites W2050050317 @default.
- W2593272302 cites W2050302634 @default.
- W2593272302 cites W2052916787 @default.
- W2593272302 cites W2053201994 @default.
- W2593272302 cites W2053453668 @default.
- W2593272302 cites W2054573424 @default.
- W2593272302 cites W2055592094 @default.
- W2593272302 cites W2057766834 @default.
- W2593272302 cites W2058855588 @default.
- W2593272302 cites W2061310579 @default.
- W2593272302 cites W2063981092 @default.
- W2593272302 cites W2066983199 @default.
- W2593272302 cites W2069186876 @default.
- W2593272302 cites W2069681977 @default.
- W2593272302 cites W2073009405 @default.
- W2593272302 cites W2074678189 @default.
- W2593272302 cites W2078350791 @default.
- W2593272302 cites W2078524519 @default.
- W2593272302 cites W2082429191 @default.
- W2593272302 cites W2083201121 @default.
- W2593272302 cites W2092044187 @default.
- W2593272302 cites W2093982682 @default.
- W2593272302 cites W2096236558 @default.
- W2593272302 cites W2097662492 @default.
- W2593272302 cites W2104048700 @default.
- W2593272302 cites W2107199945 @default.
- W2593272302 cites W2110498232 @default.
- W2593272302 cites W2114720435 @default.
- W2593272302 cites W2116556535 @default.
- W2593272302 cites W2121126184 @default.
- W2593272302 cites W2122045701 @default.
- W2593272302 cites W2127916173 @default.
- W2593272302 cites W2128274524 @default.
- W2593272302 cites W2129029307 @default.
- W2593272302 cites W2132397828 @default.