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• W2593296898 abstract "<b>Background:</b> Chronic alcohol intake impacts skin directly, through organ dysfunction or by modifying preexisting dermatoses. However, dermatoses afflicting chronic alcoholics figure in a few studies only. <b>Aim:</b> This study aims to correlate the spectrum of dermatoses in chronic alcoholics with the quantum/duration of alcohol intake and raised liver transaminases. <b>Materials and Methods:</b> Adult males, totaling 196, ascertained to fulfill the Royal College of Psychiatry criteria for chronic alcoholism by the de-addiction center and referred for dermatological consult were enrolled as cases, and similar number of age-/sex-matched teetotallers, as controls. Data emanating from detailed history, clinical examination, and routine liver functions tests were summarized and subsequently analyzed, including statistically using the Chi-square, independent “<i>t</i>” and Spearman's rank correlation tests, and compared with data from previous studies. <b>Results:</b> Majority (104) drank 41–50 units of alcohol/week since 3–40 (mean: 20.01 ± 9.322) years. Generalized pruritus (odds ratio [OR]: 31.15, <i>P</i> < 0.001), xerosis (OR: 3.62, <i>P</i> = 0.008), and seborrheic dermatitis (OR: 12.26, <i>P</i> < 0.001) were significantly more common in cases than controls. Infections (73; 37.2%), eczemas (45; 22.9%), and generalized hyperpigmentation (28; 14.2%) were the major presenting complaints. Spider nevi, gynecomastia, and pellagroid dermatitis were present in 34 (17.3%), 19 (9.7%), and 8 (4.1%) respectively exclusively in cases only. Commonly seen systemic abnormalities were an alcoholic liver disease (45; 22.9%), diabetes mellitus (23; 11.7%), and peripheral neuropathy (19; 9.7%). <b>Conclusion:</b> Knowledge of cutaneous manifestations of chronic alcoholism could prompt in-depth history taking of alcohol intake, lead to specialist referral and thereby enable timely de-addiction, hopefully before serious adversities in the chronic alcoholics." @default.
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• W2593296898 date "2017-01-01" @default.
• W2593296898 modified "2023-10-16" @default.
• W2593296898 title "Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study" @default.
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• W2593296898 doi "https://doi.org/10.4103/ijd.ijd_348_16" @default.
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