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• W2593440079 endingPage "182" @default.
• W2593440079 startingPage "143" @default.
• W2593440079 abstract "Biofuel production from lignocellulosic biomass helps to mitigate climate change and alleviate our reliance on fossil fuels. Great efforts have been made to produce biofuels in an economical way. However, high cost is still a major limitation for industrial production of biofuels. In this context, consolidated bioprocessing (CBP) renders a possible strategy to lower the total cost by integrating enzyme production, sugar release, and biofuel fermentation into a single unit operation. A robust CBP system entails an efficient enzyme system to liberate sugars from lignocellulosic biomass and for conversion of both hexoses and pentoses into desired biofuels with satisfying yield and productivity. It is quite difficult for a single wild-type microorganism to perform several different tasks simultaneously without compromising conversion efficiency. Metabolically engineered microbes, microbial consortia, or combination of these two approaches may outperform a single wild-type CBP strain. Engineering a single strain or consortia with desired traits requires detailed knowledge of mechanisms of enzyme action, deep insights into the interaction between different enzymes and discovery of novel metabolic pathways and enzymes. This review covers enzyme systems involved in CBP, potential wild-type CBP strains, strategies for engineering a CBP strain or consortium, as well as major barriers for conducting CBP." @default.
• W2593440079 created "2017-03-16" @default.
• W2593440079 creator A5050813031 @default.
• W2593440079 creator A5059122082 @default.
• W2593440079 creator A5082424766 @default.
• W2593440079 date "2017-01-01" @default.
• W2593440079 modified "2023-10-17" @default.
• W2593440079 title "Consolidated Bioprocessing Systems for Cellulosic Biofuel Production" @default.
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