Matches in SemOpenAlex for { <https://semopenalex.org/work/W2593686282> ?p ?o ?g. }
- W2593686282 endingPage "362" @default.
- W2593686282 startingPage "353" @default.
- W2593686282 abstract "Summary Obesity is a very common condition; however, the effect of excess body weight on the appropriate dose of immunoglobulin has not been defined empirically. The proposed pharmacokinetic differences between lean and obese patients and the opportunity to reduce costs has led to the proposition that obese patients should receive proportionally lower doses of immunoglobulin once a certain threshold is reached. Here the theoretical factors which could affect dosing in obese patients are considered alongside the available empirical evidence. The available evidence indicates that obesity may affect the pharmacokinetics of immunoglobulin; however, the effect is likely to be too small to have a clinically important effect on dosing. Wide interpatient individuality and highly variable clinical need mean that obesity should not play a major factor in dosing considerations. However, patients who are obese are more likely to have multiple cardiovascular risk factors and their weight indicates a large dose. This puts these patients at a higher risk of adverse reactions, and therefore caution is advised." @default.
- W2593686282 created "2017-03-16" @default.
- W2593686282 creator A5077787146 @default.
- W2593686282 date "2017-04-17" @default.
- W2593686282 modified "2023-10-18" @default.
- W2593686282 title "Considerations for dosing immunoglobulin in obese patients" @default.
- W2593686282 cites W1513833217 @default.
- W2593686282 cites W1538662871 @default.
- W2593686282 cites W1549201848 @default.
- W2593686282 cites W1588864270 @default.
- W2593686282 cites W1610655014 @default.
- W2593686282 cites W1696909045 @default.
- W2593686282 cites W1861370004 @default.
- W2593686282 cites W1892457185 @default.
- W2593686282 cites W1896431567 @default.
- W2593686282 cites W1925685882 @default.
- W2593686282 cites W1965138831 @default.
- W2593686282 cites W1969371715 @default.
- W2593686282 cites W1969968719 @default.
- W2593686282 cites W1970875728 @default.
- W2593686282 cites W1979259778 @default.
- W2593686282 cites W1979859610 @default.
- W2593686282 cites W1988239300 @default.
- W2593686282 cites W2008869160 @default.
- W2593686282 cites W2010957046 @default.
- W2593686282 cites W2011193200 @default.
- W2593686282 cites W2023733169 @default.
- W2593686282 cites W2035451300 @default.
- W2593686282 cites W2046654995 @default.
- W2593686282 cites W2047134888 @default.
- W2593686282 cites W2047758332 @default.
- W2593686282 cites W2057695882 @default.
- W2593686282 cites W2057823893 @default.
- W2593686282 cites W2059714811 @default.
- W2593686282 cites W2064394906 @default.
- W2593686282 cites W2069978926 @default.
- W2593686282 cites W2070861981 @default.
- W2593686282 cites W2071079524 @default.
- W2593686282 cites W2076633494 @default.
- W2593686282 cites W2079678184 @default.
- W2593686282 cites W2082465093 @default.
- W2593686282 cites W2087706636 @default.
- W2593686282 cites W2088836336 @default.
- W2593686282 cites W2094656159 @default.
- W2593686282 cites W2096170273 @default.
- W2593686282 cites W2101070657 @default.
- W2593686282 cites W2102224274 @default.
- W2593686282 cites W2103369491 @default.
- W2593686282 cites W2108102649 @default.
- W2593686282 cites W2110222320 @default.
- W2593686282 cites W2112599673 @default.
- W2593686282 cites W2117004364 @default.
- W2593686282 cites W2122099202 @default.
- W2593686282 cites W2134565902 @default.
- W2593686282 cites W2139434705 @default.
- W2593686282 cites W2143104968 @default.
- W2593686282 cites W2145456795 @default.
- W2593686282 cites W2153688489 @default.
- W2593686282 cites W2154640984 @default.
- W2593686282 cites W2155671289 @default.
- W2593686282 cites W2194885584 @default.
- W2593686282 cites W2253670074 @default.
- W2593686282 cites W2274414358 @default.
- W2593686282 cites W2296252503 @default.
- W2593686282 cites W2307281814 @default.
- W2593686282 cites W2336455319 @default.
- W2593686282 cites W2339765445 @default.
- W2593686282 cites W2343256546 @default.
- W2593686282 cites W2407256458 @default.
- W2593686282 cites W2413515030 @default.
- W2593686282 cites W2419576122 @default.
- W2593686282 cites W2434130898 @default.
- W2593686282 cites W2465216090 @default.
- W2593686282 cites W2469272949 @default.
- W2593686282 cites W2476059591 @default.
- W2593686282 cites W2519181983 @default.
- W2593686282 cites W4249727000 @default.
- W2593686282 cites W814161466 @default.
- W2593686282 doi "https://doi.org/10.1111/cei.12955" @default.
- W2593686282 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5422718" @default.
- W2593686282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28263379" @default.
- W2593686282 hasPublicationYear "2017" @default.
- W2593686282 type Work @default.
- W2593686282 sameAs 2593686282 @default.
- W2593686282 citedByCount "28" @default.
- W2593686282 countsByYear W25936862822017 @default.
- W2593686282 countsByYear W25936862822018 @default.
- W2593686282 countsByYear W25936862822019 @default.
- W2593686282 countsByYear W25936862822020 @default.
- W2593686282 countsByYear W25936862822021 @default.
- W2593686282 countsByYear W25936862822022 @default.
- W2593686282 countsByYear W25936862822023 @default.
- W2593686282 crossrefType "journal-article" @default.
- W2593686282 hasAuthorship W2593686282A5077787146 @default.
- W2593686282 hasBestOaLocation W25936862821 @default.
- W2593686282 hasConcept C112705442 @default.
- W2593686282 hasConcept C126322002 @default.
- W2593686282 hasConcept C159654299 @default.