FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2593809087> ?p ?o ?g. }

• W2593809087 endingPage "44" @default.
• W2593809087 startingPage "38" @default.
• W2593809087 abstract "Low omega-3 polyunsaturated fatty acid (PUFA) levels are seen in major depression. We examined effects of six weeks of fish oil supplementation on clinical characteristics in 16 patients with symptomatic major depressive disorder, and tested plasma phospholipid levels of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) as correlates of clinical response. Depression symptoms improved after supplementation (p=0.007). The reduction in depression severity was not predicted by baseline PUFA levels but did exhibit a relationship with endpoint PUFAs, correlating negatively with DHA as a percentage of plasma phospholipids (DHA%; R2=0.60, p=0.004), adjusting for endpoint EPA%; and correlating positively with endpoint EPA% (R2=0.58, p=0.007), adjusting for endpoint DHA%. Thus, the higher the proportion of DHA to EPA, the greater the reduction in depression severity (r=−0.43, p=0.097). Five patients showed a decrease of >50% on the 17-item Hamilton Depression Rating Scale and a final score <7 and were thus not only responders but met standard criteria for remission, and were distinguished from non-responders by higher levels of DHA% (p=0.03). This pilot study suggests that post-supplementation DHA% levels may be a necessary target for antidepressant response to fish oil, and that this may depend to some extent on the efficacy of EPA conversion to DHA." @default.
• W2593809087 created "2017-03-16" @default.
• W2593809087 creator A5025991600 @default.
• W2593809087 creator A5030014983 @default.
• W2593809087 creator A5042946559 @default.
• W2593809087 creator A5053352130 @default.
• W2593809087 creator A5060361199 @default.
• W2593809087 creator A5062214025 @default.
• W2593809087 creator A5078850017 @default.
• W2593809087 date "2017-04-01" @default.
• W2593809087 modified "2023-10-16" @default.
• W2593809087 title "Lipid correlates of antidepressant response to omega-3 polyunsaturated fatty acid supplementation: A pilot study" @default.
• W2593809087 cites W1510262958 @default.
• W2593809087 cites W1548073962 @default.
• W2593809087 cites W1744869158 @default.
• W2593809087 cites W1930406775 @default.
• W2593809087 cites W1950772524 @default.
• W2593809087 cites W1964889049 @default.
• W2593809087 cites W1974422835 @default.
• W2593809087 cites W1974514273 @default.
• W2593809087 cites W1975109347 @default.
• W2593809087 cites W1978358834 @default.
• W2593809087 cites W1978962043 @default.
• W2593809087 cites W1979122474 @default.
• W2593809087 cites W1980568154 @default.
• W2593809087 cites W1983653836 @default.
• W2593809087 cites W1986373853 @default.
• W2593809087 cites W1987155494 @default.
• W2593809087 cites W1991279927 @default.
• W2593809087 cites W1992677117 @default.
• W2593809087 cites W1996644850 @default.
• W2593809087 cites W2003494755 @default.
• W2593809087 cites W2003982930 @default.
• W2593809087 cites W2005455004 @default.
• W2593809087 cites W2019856631 @default.
• W2593809087 cites W2021596625 @default.
• W2593809087 cites W2024698600 @default.
• W2593809087 cites W2036594324 @default.
• W2593809087 cites W2039066744 @default.
• W2593809087 cites W2039873647 @default.
• W2593809087 cites W2042223411 @default.
• W2593809087 cites W2042630135 @default.
• W2593809087 cites W2046473477 @default.
• W2593809087 cites W2047790936 @default.
• W2593809087 cites W2051707350 @default.
• W2593809087 cites W2053612684 @default.
• W2593809087 cites W2058759125 @default.
• W2593809087 cites W2065916400 @default.
• W2593809087 cites W2069184109 @default.
• W2593809087 cites W2075359481 @default.
• W2593809087 cites W2077794554 @default.
• W2593809087 cites W2089036448 @default.
• W2593809087 cites W2101644352 @default.
• W2593809087 cites W2104285446 @default.
• W2593809087 cites W2109225320 @default.
• W2593809087 cites W2117184875 @default.
• W2593809087 cites W2117752152 @default.
• W2593809087 cites W2117884125 @default.
• W2593809087 cites W2119516214 @default.
• W2593809087 cites W2129643943 @default.
• W2593809087 cites W2132674183 @default.
• W2593809087 cites W2133830907 @default.
• W2593809087 cites W2133998561 @default.
• W2593809087 cites W2135221710 @default.
• W2593809087 cites W2138825852 @default.
• W2593809087 cites W2140092500 @default.
• W2593809087 cites W2144891204 @default.
• W2593809087 cites W2145336951 @default.
• W2593809087 cites W2145465352 @default.
• W2593809087 cites W2154436564 @default.
• W2593809087 cites W2161819400 @default.
• W2593809087 cites W2162066663 @default.
• W2593809087 cites W2163651074 @default.
• W2593809087 cites W2163909470 @default.
• W2593809087 cites W2170022513 @default.
• W2593809087 cites W2187570021 @default.
• W2593809087 cites W2217834297 @default.
• W2593809087 cites W2236483702 @default.
• W2593809087 cites W2289943296 @default.
• W2593809087 cites W2296080179 @default.
• W2593809087 cites W2298125421 @default.
• W2593809087 cites W2317934215 @default.
• W2593809087 cites W2342282778 @default.
• W2593809087 cites W2531210989 @default.
• W2593809087 doi "https://doi.org/10.1016/j.plefa.2017.03.004" @default.
• W2593809087 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5487266" @default.
• W2593809087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28410668" @default.
• W2593809087 hasPublicationYear "2017" @default.
• W2593809087 type Work @default.
• W2593809087 sameAs 2593809087 @default.
• W2593809087 citedByCount "17" @default.
• W2593809087 countsByYear W25938090872018 @default.
• W2593809087 countsByYear W25938090872019 @default.
• W2593809087 countsByYear W25938090872020 @default.
• W2593809087 countsByYear W25938090872021 @default.
• W2593809087 countsByYear W25938090872022 @default.
• W2593809087 countsByYear W25938090872023 @default.
• W2593809087 crossrefType "journal-article" @default.

• next