Matches in SemOpenAlex for { <https://semopenalex.org/work/W2593840352> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2593840352 abstract "Carbapenemase-producing Enterobacteriaceae (CPE), particularly carbapenemase-producing Klebsiella pneumoniae isolates, are important causative agents of nosocomial infections associated with significant mortality rates mostly in critical wards. The rapid detection and typing of these strains is critical either for surveillance purposes and to prevent outbreaks and optimize antibiotic therapy. In this study, the MALDI-TOF MS method was used to detect rapidly these isolates from blood cultures (BCs) and to obtain proteomic profiles enable to discriminate between carbapenemase-producing and non-carbapenemase-producing strains. Fifty-five K. pneumoniae strains were tested. Identification and carbapenemase-production detection assay using Ertapenem were performed both from bacterial pellets extracted directly from BCs flasks and from subcultures of these strains. For all isolates, a complete antimicrobial susceptibility testing and a genotypic characterization were performed. We found 100% agreement between the carbapenemase-producing profile generated by MALDI TOF MS and that obtained using conventional methods. The assay detected and discriminated different carbapenemase-producing K. pneumoniae isolates within 30 min to 3 h after incubation with Ertapenem. MALDI-TOF MS is a promising, rapid and economical method for the detection of carbapenemase-producing K. pneumoniae strains that could be successfully introduced into the routine diagnostic workflow of clinical microbiology laboratories." @default.
- W2593840352 created "2017-03-16" @default.
- W2593840352 creator A5002661463 @default.
- W2593840352 creator A5008361911 @default.
- W2593840352 creator A5028943651 @default.
- W2593840352 creator A5055601928 @default.
- W2593840352 creator A5088930348 @default.
- W2593840352 date "2017-03-08" @default.
- W2593840352 modified "2023-09-26" @default.
- W2593840352 title "Rapid detection of carbapenemase-producing Klebsiella pneumoniae strains derived from blood cultures by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS)" @default.
- W2593840352 cites W1856472616 @default.
- W2593840352 cites W1856609834 @default.
- W2593840352 cites W2005529974 @default.
- W2593840352 cites W2024237409 @default.
- W2593840352 cites W2049294434 @default.
- W2593840352 cites W2057684478 @default.
- W2593840352 cites W2063910158 @default.
- W2593840352 cites W2065337857 @default.
- W2593840352 cites W2087126312 @default.
- W2593840352 cites W2103658533 @default.
- W2593840352 cites W2115035455 @default.
- W2593840352 cites W2115445096 @default.
- W2593840352 cites W2117508830 @default.
- W2593840352 cites W2118778408 @default.
- W2593840352 cites W2120600261 @default.
- W2593840352 cites W2127148897 @default.
- W2593840352 cites W2137683650 @default.
- W2593840352 cites W2145915746 @default.
- W2593840352 cites W2154556219 @default.
- W2593840352 cites W2165158988 @default.
- W2593840352 cites W2171401200 @default.
- W2593840352 cites W2400586161 @default.
- W2593840352 doi "https://doi.org/10.1186/s12866-017-0952-3" @default.
- W2593840352 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5343375" @default.
- W2593840352 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28274205" @default.
- W2593840352 hasPublicationYear "2017" @default.
- W2593840352 type Work @default.
- W2593840352 sameAs 2593840352 @default.
- W2593840352 citedByCount "36" @default.
- W2593840352 countsByYear W25938403522017 @default.
- W2593840352 countsByYear W25938403522018 @default.
- W2593840352 countsByYear W25938403522019 @default.
- W2593840352 countsByYear W25938403522020 @default.
- W2593840352 countsByYear W25938403522021 @default.
- W2593840352 countsByYear W25938403522022 @default.
- W2593840352 countsByYear W25938403522023 @default.
- W2593840352 crossrefType "journal-article" @default.
- W2593840352 hasAuthorship W2593840352A5002661463 @default.
- W2593840352 hasAuthorship W2593840352A5008361911 @default.
- W2593840352 hasAuthorship W2593840352A5028943651 @default.
- W2593840352 hasAuthorship W2593840352A5055601928 @default.
- W2593840352 hasAuthorship W2593840352A5088930348 @default.
- W2593840352 hasBestOaLocation W25938403521 @default.
- W2593840352 hasConcept C104317684 @default.
- W2593840352 hasConcept C2777058267 @default.
- W2593840352 hasConcept C2778368673 @default.
- W2593840352 hasConcept C2779375183 @default.
- W2593840352 hasConcept C2779473907 @default.
- W2593840352 hasConcept C2992965680 @default.
- W2593840352 hasConcept C501593827 @default.
- W2593840352 hasConcept C547475151 @default.
- W2593840352 hasConcept C55493867 @default.
- W2593840352 hasConcept C86803240 @default.
- W2593840352 hasConcept C89423630 @default.
- W2593840352 hasConcept C94665300 @default.
- W2593840352 hasConceptScore W2593840352C104317684 @default.
- W2593840352 hasConceptScore W2593840352C2777058267 @default.
- W2593840352 hasConceptScore W2593840352C2778368673 @default.
- W2593840352 hasConceptScore W2593840352C2779375183 @default.
- W2593840352 hasConceptScore W2593840352C2779473907 @default.
- W2593840352 hasConceptScore W2593840352C2992965680 @default.
- W2593840352 hasConceptScore W2593840352C501593827 @default.
- W2593840352 hasConceptScore W2593840352C547475151 @default.
- W2593840352 hasConceptScore W2593840352C55493867 @default.
- W2593840352 hasConceptScore W2593840352C86803240 @default.
- W2593840352 hasConceptScore W2593840352C89423630 @default.
- W2593840352 hasConceptScore W2593840352C94665300 @default.
- W2593840352 hasIssue "1" @default.
- W2593840352 hasLocation W25938403521 @default.
- W2593840352 hasLocation W25938403522 @default.
- W2593840352 hasLocation W25938403523 @default.
- W2593840352 hasLocation W25938403524 @default.
- W2593840352 hasLocation W25938403525 @default.
- W2593840352 hasOpenAccess W2593840352 @default.
- W2593840352 hasPrimaryLocation W25938403521 @default.
- W2593840352 hasRelatedWork W1980009488 @default.
- W2593840352 hasRelatedWork W1984501836 @default.
- W2593840352 hasRelatedWork W2110241095 @default.
- W2593840352 hasRelatedWork W2130148142 @default.
- W2593840352 hasRelatedWork W2150670612 @default.
- W2593840352 hasRelatedWork W2156446002 @default.
- W2593840352 hasRelatedWork W2765807259 @default.
- W2593840352 hasRelatedWork W2790937404 @default.
- W2593840352 hasRelatedWork W2945165328 @default.
- W2593840352 hasRelatedWork W3157929551 @default.
- W2593840352 hasVolume "17" @default.
- W2593840352 isParatext "false" @default.
- W2593840352 isRetracted "false" @default.
- W2593840352 magId "2593840352" @default.
- W2593840352 workType "article" @default.