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- W2594205347 abstract "Knowledge of the relevant genomic aberrations that drive a particular cancer type is necessary to accelerate efficient interpretation of genomic data and enable large-scale endeavours in precision medicine. Currently, this field is limited by the lack of focused and scalable literature curation tools that can reliably capture the required information. Here we present a knowledge-base of genes that have been described in the literature as drivers, oncogenes or tumour suppressors with respect to a specific type of cancer. We have annotated a large body of literature which reports oncogenic aberrations using a custom designed annotation tool. We then applied VERSE, an in-house relation extraction tool, to catalogue driver mutations and illustrate the ability to build a useful resource for clinical interpretation of genomic data for personalised treatment approaches." @default.
- W2594205347 created "2017-03-16" @default.
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- W2594205347 date "2016-01-01" @default.
- W2594205347 modified "2023-09-24" @default.
- W2594205347 title "CancerMine: Knowledge Base Construction for Personalised Cancer Treatment" @default.
- W2594205347 hasPublicationYear "2016" @default.
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