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- W2594303032 abstract "Abstract A fluorescent probe ( DBT ) based on conjugation of 2,3-dimethylbenzo[ d ]thiazol-3-ium iodide to 3-(benzo[ d ]thiazol-2-yl)-2-hydroxy-5-methylbenzaldehyde for the detection of sulfur dioxide derivatives (HSO 3 − /SO 3 2− ) has been developed. DBT exhibits highly selective colorimetric and ratiometric fluorescence dual response to HSO 3 − with a fluorescence detection limit of 3.50 × 10 −7 M. The HSO 3 − sensing mechanism was confirmed to undergo nucleophilic addition of HSO 3 − to alkene double bond of DBT as evidenced by 1 H NMR and HRMS analysis. The probe is MCF-7 cell permeable and applicable for fluorescence imaging of exogenous and intrinsically generated intracellular SO 2 derivatives in the living cells. Fluorescence co-localization studies reveal that DBT is a mitochondria-targetable fluorescent probe. Thus, DBT has potential application for exploring the role played by SO 2 derivatives in biology." @default.
- W2594303032 created "2017-03-16" @default.
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- W2594303032 date "2017-08-01" @default.
- W2594303032 modified "2023-10-16" @default.
- W2594303032 title "A mitochondria-targetable fluorescent probe for ratiometric detection of SO2 derivatives and its application in live cell imaging" @default.
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- W2594303032 doi "https://doi.org/10.1016/j.snb.2017.03.032" @default.
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