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• W2594346557 abstract "Abstract Thiamine (vitamin B1) is essential to the health of all living organisms and deficiency has long been associated with diseases in animals such as fish, birds, alligators, and domesticated ruminant mammals. Thiamine is also implicated in several human diseases including Alzheimer's, diabetes, dementia, depression and, most notably, Wernicke–Korsakoff syndrome and Beriberi disease. Yet, highly sensitive and specific detection of thiamine remains an analytical challenge, as pM to n m levels of thiamine need to be detected in environmental and human samples, respectively, various phosphorylated variants need to be discriminated, and rapid on‐site detection would be highly desirable. Furthermore, appropriate sample preparation is mandatory, owing to the complexity of the relevant sample matrices including fish tissues, ocean water, and body fluids. This Review has two objectives. First, it provides a thorough overview of analytical techniques published for thiamine detection over the last 15 years. Second, it describes the principles of analytical approaches that are based on biorecognition and may open up new avenues for rapid and high‐throughput thiamine analysis. Most notably, periplasmic binding proteins, ribozymes, and aptamers are of particular interest, as they function as bioaffinity recognition elements that can fill an important assay technology gap, owing to the unavailability of thiamine‐specific commercial antibodies. Finally, the authors provide brief evaluations of key outcomes of the major assay concepts and suggest how innovative techniques could help develop sensitive and specific thiamine analytical test systems." @default.
• W2594346557 created "2017-03-16" @default.
• W2594346557 creator A5016262011 @default.
• W2594346557 creator A5039974328 @default.
• W2594346557 creator A5042428271 @default.
• W2594346557 creator A5045398461 @default.
• W2594346557 creator A5060700361 @default.
• W2594346557 creator A5083818808 @default.
• W2594346557 date "2017-03-08" @default.
• W2594346557 modified "2023-09-30" @default.
• W2594346557 title "Thiamine Assays—Advances, Challenges, and Caveats" @default.
• W2594346557 cites W118443089 @default.
• W2594346557 cites W1490400638 @default.
• W2594346557 cites W1525796434 @default.
• W2594346557 cites W1541702708 @default.
• W2594346557 cites W156560493 @default.
• W2594346557 cites W1583300816 @default.
• W2594346557 cites W175291990 @default.
• W2594346557 cites W1824341384 @default.
• W2594346557 cites W1891911041 @default.
• W2594346557 cites W1931599004 @default.
• W2594346557 cites W1942446603 @default.
• W2594346557 cites W1965187563 @default.
• W2594346557 cites W1965720511 @default.
• W2594346557 cites W1968539356 @default.
• W2594346557 cites W1970437861 @default.
• W2594346557 cites W1972081063 @default.
• W2594346557 cites W1974892165 @default.
• W2594346557 cites W1979483886 @default.
• W2594346557 cites W1980451473 @default.
• W2594346557 cites W1984167957 @default.
• W2594346557 cites W1984844168 @default.
• W2594346557 cites W1988251333 @default.
• W2594346557 cites W1989959388 @default.
• W2594346557 cites W1996531094 @default.
• W2594346557 cites W1997989260 @default.
• W2594346557 cites W1998341894 @default.
• W2594346557 cites W2004466182 @default.
• W2594346557 cites W2004936060 @default.
• W2594346557 cites W2005166978 @default.
• W2594346557 cites W2015755112 @default.
• W2594346557 cites W2021165169 @default.
• W2594346557 cites W2021911011 @default.
• W2594346557 cites W2034624937 @default.
• W2594346557 cites W2037390511 @default.
• W2594346557 cites W2038109559 @default.
• W2594346557 cites W2039520611 @default.
• W2594346557 cites W2044498724 @default.
• W2594346557 cites W2046461915 @default.
• W2594346557 cites W2050834877 @default.
• W2594346557 cites W2051279046 @default.
• W2594346557 cites W2052493403 @default.
• W2594346557 cites W2053758691 @default.
• W2594346557 cites W2055867625 @default.
• W2594346557 cites W2056008471 @default.
• W2594346557 cites W2057040611 @default.
• W2594346557 cites W2058906934 @default.
• W2594346557 cites W2059933411 @default.
• W2594346557 cites W2063755147 @default.
• W2594346557 cites W2063770405 @default.
• W2594346557 cites W2067510270 @default.
• W2594346557 cites W2067556577 @default.
• W2594346557 cites W2068156590 @default.
• W2594346557 cites W2069843381 @default.
• W2594346557 cites W2070210595 @default.
• W2594346557 cites W2075577061 @default.
• W2594346557 cites W2076775806 @default.
• W2594346557 cites W2077674691 @default.
• W2594346557 cites W2082884386 @default.
• W2594346557 cites W2083620413 @default.
• W2594346557 cites W2084976083 @default.
• W2594346557 cites W2085822960 @default.
• W2594346557 cites W2086775742 @default.
• W2594346557 cites W2086819065 @default.
• W2594346557 cites W2087127406 @default.
• W2594346557 cites W2089487117 @default.
• W2594346557 cites W2089840436 @default.
• W2594346557 cites W2090473875 @default.
• W2594346557 cites W2099378111 @default.
• W2594346557 cites W2111056884 @default.
• W2594346557 cites W2111307528 @default.
• W2594346557 cites W2114501046 @default.
• W2594346557 cites W2115568341 @default.
• W2594346557 cites W2117854740 @default.
• W2594346557 cites W2121396131 @default.
• W2594346557 cites W2140150201 @default.
• W2594346557 cites W2142375525 @default.
• W2594346557 cites W2142527721 @default.
• W2594346557 cites W2148481234 @default.
• W2594346557 cites W2162735935 @default.
• W2594346557 cites W2166783499 @default.
• W2594346557 cites W2170221853 @default.
• W2594346557 cites W2208098550 @default.
• W2594346557 cites W2266673036 @default.
• W2594346557 cites W2281187903 @default.
• W2594346557 cites W2296053803 @default.
• W2594346557 cites W2306514611 @default.
• W2594346557 cites W2344706780 @default.

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