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• W2594548019 abstract "The on-going integration of systems biology functionalities into all aspects of pharmacology and toxicology has resulted in a more network-based focus, which continues to enhance the understanding of therapeutic efficacious and adverse events both at the early and late stages of research and development. These advances have been coupled with the public availability of large datasets of information and new modeling approaches that have enhanced the ability to understand toxicological events and effects at multiple biological levels. Systems toxicology approaches are also being used in the safer design of chemicals and identification of safer alternatives, which are major parts of global green chemistry initiatives. In environmental toxicology, a major advance associated with these new efforts has been the establishment of the adverse outcome pathway concept and modeling approaches used for the identification of hazards and defining risk assessments for the large number of environmental chemicals, most with very few supporting data." @default.
• W2594548019 created "2017-03-16" @default.
• W2594548019 creator A5068055736 @default.
• W2594548019 date "2017-03-03" @default.
• W2594548019 modified "2023-09-23" @default.
• W2594548019 title "Systems Biology Approaches in Pharmacology and Toxicology" @default.
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• W2594548019 doi "https://doi.org/10.1039/9781782623731-00001" @default.
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